1. Extracellular Vesicles (EVs) may repair cardiac tissue after damage

    Exosomes are nanovesicles released from cells through exocytosis and are known mediators of proximal and distant cell-to-cell signaling. Still little is known and written about cardiac exosomes, although Gupta and Knowlton described exosomes containing HSP60 in 2007 [1].
  2. Exosomes and Breast Cancer

    Breast cancer will affect 1 in 8 woman during their lifetime and is the most common cancer among females worldwide, according to the World Health Organization. Breast cancer occurs when malignant cells are formed in the mammary tissue and spreads to form tumors.
  3. Exosomes and Cancer: the Inside of Intrigue

    The cellular process of exosome shedding turns out to have a wide range of important regulatory functions. Their original discovery in sheep reticulocyte maturation gave rise to the idea that exosomes may function as a trash bin for unnecessary and redundant proteins, which, at the time, offered an alternative pathway for lysosome degradation [1]. Nevertheless, most attention has been given to their role in supporting the immune system. Functional in vivo experiments have shown that exosomes affect the immune system by expressing and processing surface antigens.
  4. Exosomal Protein Profiling Reveals Biomarkers for Prostate Cancer

    The male prostate gland is a walnut-sized structure responsible for controlling the flow of urine and adding fluid to contribute to the total volume of semen produced. Prostate cancer is the second leading cause of death among men, with 1 in 7 men being diagnosed in his lifetime.
  5. Exosomal microRNA: the answer for Multiple Sclerosis?

    The inflammatory disease, Multiple Sclerosis (MS), occurs when the body's own immune system attacks the myelin protective sheath covering nerve cells in the brain and spinal cord. Nerve cells are crucial for communication between the nervous system and therefore the irreversible damage results in a range of symptoms depending on the amount of nerves affected. Physical and mental symptoms are...
  6. Exosome Commercialization and Product Development

    Exosomes can be thought of as tiny packages of potential. Given their intricate construction, exosomes may possess a much more powerful influence on the physiology of the cells they encounter than other solitary mediators, such as hormones, lipids, or cytokines.
  7. Exosome Analysis in Fruit Fly Reproduction

    Scientists at the University of Oxford have recently discovered the presence of exosomes in males' seminal fluid in Drosophila melanogaster (fruit fly) which helps to ensure their reproductive success with females [1].
  8. Exosome Biomarker for Alzheimer's Disease

    Alzheimer’s disease is a neurodegenerative disorder, involving memory loss which progressively worsens, eventually leading to death. Currently there is no cure and diagnosis is commonly based on a person’s family history or expensive and intrusive detection methods.
  9. Cellular Exosomes for the 21st Century - Overview - part 1

    Discovered nearly 30 years ago, exosomes are now being implicated in one of the most important and promising breakthroughs in medical therapy yet. A quick glance in PubMed reveals over ~3,000 journal references since their discovery in 1983.
  10. AG Scientific's Science Photo of the Week

    This week's science photo is a three wavelength composite view of the X1.6-class solar flare captured at it's peak on Wednesday, September 10, by NASA's Solar Dynamics Observatory. The sun unleashed a medium-sized flare earlier on Monday, Sept. 8 before reaching the pinnacle of it's solar episode two days later.

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