1. Zinc-Finger Nucleases: Expanding the Gene Editor's Tool Kit

    Zinc finger nucleases (ZFNs) have become useful reagents when it comes to manipulating the genomes in plants and animals. As a result, they are becoming increasingly widespread throughout academic campuses and industrial applications worldwide.
  2. Genome Engineering using CRISPR (Cas9)

    DNA (Deoxyribonucleic Acid) is often referred to as the blueprint for life. This is because DNA is made up of genes, which encode for the information required to produce functional proteins. describe the imageFor decades it was believed that only higher order, multi-cellular life possessed the cellular machinery necessary to provide its host with adaptive immunity. We now know that DNA is routinely edited in bacteria as part of their own adaptive immune response, which is made possible largely because of an enzyme called CRISPR – pronounced ‘crisper’.
  3. Circulating Glioma Biomarkers: Agents of Detection

    High-grade gliomas represent one of the most aggressive and treatment-resistant types of human brain cancer, with a median survival rate of only 14.6 months for patients with grade IV glioma (glioblastoma) [1,2].
  4. Drug Resistant Pathogens a growing problem, study suggests

    While some human activities are slowing the spread of certain infectious diseases, some have promoted them. Advances in public sanitation, hygiene, and medicine have all helped to prevent the unnecessary suffering of illness. Effective vaccines and worldwide vaccination programs have severely reduced many types of adult and childhood infections such as mumps and measles, while smallpox and polio are rarities...
  5. How Chemokines are unraveling the causes of disease

    Over the course of our life, our immune system will fight off countless infections from a variety of bacteria, viruses and parasites, in addition to protecting us from cancer and healing damaged tissue. It’s a pretty remarkable system, accounting for over 85% of our genome, and yet is only possible because of a highly complex specialized cell types and backup response mechanisms.
  6. Tracking Cancer Immunotherapy: Dendritic Cell-Derived Exosomes

    Dendritic cells (DCs) are essential in order to combat invading viruses and trigger antiviral responses. New immunotherapy techniques to fight cancer are based on a DC’s ability to capture foreign antigens and innately present them to specific cytotoxic T cells.
  7. Colon Cancer: Exosomal Diagnostic Biomarkers and Therapeutics

    Colon cancer and cancer affecting the last few inches of the colon are collectively named colorectal cancer. In its early stages no symptoms may exist, creating a strong emphasis on regular patient screening. With interest increasing about the use of exosomal miRNA as a biomarker for cancer, Ogata-Kawata and colleagues decided to carry out research on the possible link between pathological changes witnessed in patients affected by colorectal cancer and their specific exosomal miRNA levels [1].

7 Item(s)

To Top