1. Cefsulodin Sodium: FAQs, Protocols and Applications

    Cefsulodin Sodium: FAQs, Protocols and Applications
    Cefsulodin is a semi-synthetic third generation cephalosporin antibiotic with a structure similar to penicillins and beta-lactams. Cefsulodin is used by the water and dairy industries to test the quality of their products. AG Scientific continues to provide top quality testing reagents and supplies to water and dairy producers around the world. This article includes a list of our FAQs regarding...
  2. Penicillin: How We Made a Global Savior

    Penicillin: How We Made a Global Savior
    The name 'antibiotic' was first given to the drugs that exhibit 'antibiosis' (meaning 'against life'), by Selman Waksman in 1942. After Vincenzo Tiberio discovered a mold (penicillium) in a well that displayed antibacterial, it led others to find the reasoning behind this. However, it was Alexander Fleming's (above) observations of fungus working against bacteria and concluded that it was due to the antibacterial compound, Penicillin.
  3. AG Scientific Offers Bulk Proteinase K Packaging & Labeling Services

    AG Scientific Offers Bulk Proteinase K Packaging & Labeling Services
    AG Scientific is the established leader in Proteinase K bulk supply, catalog packaging, custom size vialing and private labeling services. We guarantee the following:
  4. How Safe Is Your Water?

    How Safe Is Your Water?
      Water Contamination The common causes of acute diarrhea are viruses and bacteria. Diarrhea is a symptom of infections caused by a host of bacterial, viral and parasitic organisms, most of which are spread by feces-contaminated water. Escherichia coli (E. coli) are a large and diverse group of bacteria. Although most strains of E. coli are harmless, others can make...
  5. Water Quality and Dairy Quality Testing - FAQs

    Water Quality and Dairy Quality Testing - FAQs
    Whenever you pour yourself a glass of water, it may appear to be clean and you might expect the water quality to be safe. However, many sources of water contain dissolved minerals, organic compounds, or live pathogens at harmful levels. Other minerals in your water could also result in an unpleasant taste, odors, and could stain bathroom fixtures or your...
  6. Proteinase K Applications in Prion-Related Diseases

    Proteinase K Applications in Prion-Related Diseases
    Proteinase K degrades almost every protein and inactivates rapidly enzymatic activities under a broad range of conditions (SDS, Urea, pH 4 -12). The enzyme is used for the isolation of clean and native genomic DNA and RNA in order to guarantee PCR based detection.
  7. Beta-Lactamase Hybrid Proteins

    Beta-Lactamase Hybrid Proteins
    Introduction Beta-lactam antibiotics are used to treat a broad spectrum of Gram-positive and Gram-negative bacteria.   β-lactam antibiotics target the penicillin-binding proteins (PBPs) - a group of enzymes found attached in the cell membrane, which are involved in the cross-linking of the bacterial cell wall. The β-lactam ring portion of this group of antibiotics binds to these different PBPs, rendering them...
  8. Carbenicillin Antibiotic - Top 7 FAQs

    Carbenicillin Antibiotic - Top 7 FAQs
    Using carbenicillin antibiotics in your research? Get to know these top frequently asked questions!   1. What is Carbenicillin? Carbenicillin, also known as carboxybenzylpenicillin, is a member of the penicillin β-lactam antibiotics. Unlike most β-lactams, carbenicillin disodium is limited to primarily gram-negative bacteria including Pseudomonas aeruginosa and common enteric species. It can be used in selection protocols and is often preferred...
  9. Protease Enzymes - Common Applications

    Protease Enzymes - Common Applications
    Introduction to Protease Enzymes There are five families of proteases in which serine (eg: proteinase K/protease K/endopeptidase K), threonine, cysteine, aspartic or metallic groups play a primary catalytic role. Protease enzymes break the long chain-like molecules of proteins into shorter fragments. They are ubiquitous, found in all living organisms, and are essential for cell growth and differentiation. While protease enzymes...
  10. Part 2: Solving Mysteries with Trypsin and Proteinase K

    Part 2: Solving Mysteries with Trypsin and Proteinase K
    In Part 1, we discussed using trypsin on bone specimens as a cleaning alternative to sanding in preparation for DNA extraction. In this second part of the series, we cover the details of attaining a higher yield of DNA using proteinase K. Proteinase K for Higher DNA Yield from Bone Specimens DNA in bone is located in the osteocytes (Hochmeister et...

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