For the last 15 years, A.G. Scientific has been a leading supplier of Daptomycin. We offer a range of catalog sizes, as well as, multi-kilogram quantities for bulk applications. Additionally, we provide a full service of bottling, sterile formulations, custom packaging, as well as, comprehensive private labeling capabilities.

Bestatin, also known as Ubenimex, is a competitive protease inhibitor. It is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. It is being studied for use in the treatment of acute myelocytic leukemia.

β-Lactamases continue to be the leading cause of resistance to β-lactam antibiotics among gram-negative bacteria. In recent years there has been an increased incidence and prevalence of extended-spectrum β-lactamases (ESBLs), enzymes that hydrolyze and cause resistance to oxyimino-cephalosporins and aztreonam.

IPTG is a molecular biology reagent utilized in cloning experiments. This compound is used as a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lacoperon. Unlike allolactose, the IPTG sulfur (S) atom creates a chemical bond which is non-hydrolyzable by the cell, preventing the cell from "eating up" or degrading the inductant; therefore the IPTG concentration remains constant.

About PMSF Inhibitor An important serine protease inhibitor commonly utilized by biochemists and researchers, phenylmethylsulfonyl fluoride (PMSF) is often used to prepare cell lysates, helping to preserve critical samples. Acting as a non-specific inhibitor, PMSF is often used to protect samples against the digestive functions of proteases, such as trypsin, chymotrypsin, and thrombin, as well as other enzymes. It is...

or the last 18 years, AG Scientific has been a leading manufacturer, retail supplier and wholesaler of g-418, Geneticin®. Our success with a combination of fermentation & synthesis that has allowed us to build a catalog of over 180 antibiotics and a customer base of researchers, catalog biochemical distributors and cell media manufacturers worldwide.

Ionophores are molecules that facilitate ion passage in or out of cell membranes. Ion carrier: A substance that can transfer ions from a hydrophilic medium, such as water, into a hydrophobic medium, i.e a biological membrane, where the ions typically would not be soluble.

Cell death has traditionally been subdivided into regulated (apoptosis) and unregulated (necrosis) forms. While apoptosis has always been recognized to be a pathway of highly orchestrated signaling events, necrosis or necrotic cell death is known as a fortuitous and unregulated means of cell death that is induced by nonspecific and nonphysiological stress.

Valinomycin is a potent antibiotic which acts as a potassium (K+) ionophore. Induces K+ conductivity in cell membranes. Also active in vitro against Mycobacterium Tuberculosis, and as an apoptosis inducer. Valinomycin is obtained from the cells of several Streptomyces strains, among which "S. tsusimaensis" and S. fulvissimus.

Blasticidin S is an antibiotic used by scientists in bio-research to select cells modified by genetic engineering. It inhibits the growth of a wide range of prokaryotic and eukaryotic cells by interfering with protein synthesis. Blasticidin S allows the selection and maintenance of cells expressing the blasticidin-resistance gene.