1. Pathology Research Using Mitophagy Modulators

    Pathology Research Using Mitophagy Modulators
    Pathology Research Using Mitophagy Modulators When you hear “small things with big impact”, do you immediately think of mitochondria and mitophagy modulators? Probably not! But these little organelles are champions of cell regulation.  Among their functions is regulating the energy of the cell as well as cell death. And just as mitochondria are responsible for cell function, mitophagy is responsible...
  2. Hydroxychloroquine: Misconceptions in the Media

    Hydroxychloroquine: Misconceptions in the Media
    Hydroxychloroquine: Misconceptions in the Media It’s hard to miss hearing the word “hydroxychloroquine” being associated with coronavirus in the news right now.  Hydroxychloroquine is being touted as a “game changer” in treating coronavirus by people in the current US administration who are not medical professionals. This drug has a similar structure to a previously established drug called CQ (N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine), which...
  3. Tunicamycin: ER Stress Inducer

    Tunicamycin: ER Stress Inducer
    Tunicamycin: ER Stress Inducer When we hear the terms cell death and endoplasmic reticulum (ER) stress, what first comes to mind?  3D illustration of protein folding Stress? Death? Two concepts that don’t exactly inspire positive thoughts.  However, in the case of the antibiotic compound tunicamycin, cell death and ER stress are the objectives.  What is Tunicamycin? Tunicamycin is an antibiotic...
  4. Daptomycin: Frequently Asked Questions - Answered!

    Daptomycin: Frequently Asked Questions - Answered!
    For the last 15 years, A.G. Scientific has been a leading supplier of Daptomycin. We offer a range of catalog sizes, as well as, multi-kilogram quantities for bulk applications. Additionally, we provide a full service of bottling, sterile formulations, custom packaging, as well as, comprehensive private labeling capabilities.
  5. Beta-Lactamase and Microbial Antibiotic Resistance

    Beta-Lactamase and Microbial Antibiotic Resistance
    β-Lactamases continue to be the leading cause of resistance to β-lactam antibiotics among gram-negative bacteria. In recent years there has been an increased incidence and prevalence of extended-spectrum β-lactamases (ESBLs), enzymes that hydrolyze and cause resistance to oxyimino-cephalosporins and aztreonam.
  6. G418 Sulfate (Geneticin): Protocols and FAQs

    G418 Sulfate (Geneticin): Protocols and FAQs
    or the last 18 years, AG Scientific has been a leading manufacturer, retail supplier and wholesaler of g-418, Geneticin®. Our success with a combination of fermentation & synthesis that has allowed us to build a catalog of over 180 antibiotics and a customer base of researchers, catalog biochemical distributors and cell media manufacturers worldwide.
  7. Ionophores: Ion Carriers and Channels for Membrane Transport

    Ionophores: Ion Carriers and Channels for Membrane Transport
    Ionophores are molecules that facilitate ion passage in or out of cell membranes. Ion carrier: A substance that can transfer ions from a hydrophilic medium, such as water, into a hydrophobic medium, i.e a biological membrane, where the ions typically would not be soluble.
  8. Valinomycin Ionophore: Frequently Asked Questions

    Valinomycin Ionophore: Frequently Asked Questions
    Valinomycin is a potent antibiotic which acts as a potassium (K+) ionophore. Induces K+ conductivity in cell membranes. Also active in vitro against Mycobacterium Tuberculosis, and as an apoptosis inducer. Valinomycin is obtained from the cells of several Streptomyces strains, among which "S. tsusimaensis" and S. fulvissimus.
  9. Blasticidin S Hydrochloride: Frequently Asked Questions

    Blasticidin S Hydrochloride: Frequently Asked Questions
    Blasticidin S is an antibiotic used by scientists in bio-research to select cells modified by genetic engineering. It inhibits the growth of a wide range of prokaryotic and eukaryotic cells by interfering with protein synthesis. Blasticidin S allows the selection and maintenance of cells expressing the blasticidin-resistance gene.
  10. Hygromycin B: Most Frequently Asked Questions

    Hygromycin B: Most Frequently Asked Questions
    A.G.Scientific emerged as a leading manufacturer and importer of Hygromycin B, an antibiotic used for gene selection. Over the past 18 years we have learned a lot about this Aminoglycosides antibiotic. It was our success with a combination of fermentation & synthesis that has allowed us to build a customer base of researchers and catalog biochemical distributors worldwide. Questions on solution storage & what are the procedures to determine toxic concentration are common to all customers of Hygromycin. So here we listed the top questions we have received from our customers.

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