1. Fighting Biofilm Formation

    Fighting Biofilm Formation
    Biofilm consists of bacterial colonies that excrete a sticky organic texture. The colonies form when a thin layer of microorganisms and proteins adhere to a surface. They may appear as a slimy film on poorly maintained poolsides, river rocks, dishes, and countertops or, in smaller forms, may be invisible to the eye. Biofilm Formation Specifically, biofilms form when groups of...
  2. Fidaxomicin for Life Science Research

    Fidaxomicin for Life Science Research
    Fidaxomicin (C52H74Cl2O18) is a member of the class of narrow spectrum macrocyclic antibiotics known as tiacumicins. The drug derives from the fermentation of tiacumicin metabolites from a soil isolate of the actinomycete Dactylosporangium aurantiacum, a Gram-positive bacterium. Scientists discovered fidaxomicin (known as lipiarmycin) in 1975, isolating the compound in pure form from Actinoplanes deccanensis. Researchers noted the antibiotic’s effectiveness in...
  3. Mitomycin C Applications in Life Sciences

    Mitomycin C Applications in Life Sciences
    Mitomycin C (C15H18N4O5) is a chemical product derived from Streptomyces caespitosus, an actinobacteria species. It appears as a blue-violet crystal or powder at room temperature. The product is soluble in water and rapidly degrades in acidic preparations. Healthcare researchers and scientists have studied and applied mitomycin C in cancer treatment for its antitumor properties. Mitomycin has become a popular chemotherapeutic...
  4. Top 10 Antibiotic Resistant Infections

    Top 10 Antibiotic Resistant Infections
    Antibiotic resistant infections arise when bacteria and other microbes develop immunity against the drugs administered against them. Infections involving antibiotic-resistant strains grow stronger over time and become increasingly difficult to treat. According to CDC reports, over 2.8 million antibiotic-resistant infections occur in the US every year and have lead to a large number of fatalities. Bacteria naturally develop immunities over...
  5. Avoiding Cross-Contamination in Antibiotic Manufacturing

    Avoiding Cross-Contamination in Antibiotic Manufacturing
    There are two major categories of antibiotics: penicillin beta-lactam and non-penicillin beta-lactam products. Research authorities have identified five primary groups under the beta-lactam category of antibiotics, including penicillins, cephalosporins, penems, carbacephems, and monobactams. Avoiding cross-contamination between penicillin and non-penicillin products remains a top concern for drug manufacturers despite the modern day success of antibiotics. Penicillin is an umbrella term for...
  6. Water Quality and Dairy Quality Testing FAQs

    Water Quality and Dairy Quality Testing FAQs
    Whenever you pour yourself a glass of water, it may appear to be clean and you might expect the water quality to be safe. However, many sources of water contain dissolved minerals, organic compounds, or live pathogens at harmful levels. Other minerals in your water could also result in an unpleasant taste, odors, and could stain bathroom fixtures or your...
  7. 7 Sources of Antibiotic Resistance

    7 Sources of Antibiotic Resistance
    The growing increase of antibiotic resistance is now a global problem. According to the National Foundation for Infectious Disease, approximately 3 million people each year struggle with infections from antibiotic resistant bacteria. About 35,000 individuals will die as a result of these infections. Antibiotic resistance is a concern for several important reasons. Illnesses such as strep throat, tuberculosis, and certain...
  8. Popular Anti-Fungal Drugs: An Overview

    Popular Anti-Fungal Drugs: An Overview
    Anti-fungal drugs play an important role in treating serious medical conditions. These drugs are used to treat primary fungal infections as well as secondary infections. Anti-fungal drugs can be administered through different channels and play a key role in keeping cancer patients and organ donors healthy. Let's examine how these drugs work and why continued research and development is so...
  9. Using Bicyclomycin to Treat Drug-Resistant Bacterial Infections

    Using Bicyclomycin to Treat Drug-Resistant Bacterial Infections
    Stating that antibiotics, first discovered in 1928 and commercially used by the 1940s, brought an unprecedented change to the world is not an overstatement. For decades now we have routinely cured illnesses and infections that were previously life-threatening. In recent years, however, bacterial infections have increasingly grown resistant to antibiotics. According to the CDC, approximately 2.8 million people each year...
  10. The SUnSET Assay: Powerful Proteomics

    The SUnSET Assay: Powerful Proteomics
    The SUnSET Assay: Powerful Proteomics Exciting advances in the study of protein synthesis and related health conditions are on the horizon! Research scientists have developed an improved process to quantify and understand the processes of protein synthesis in singular eukaryotic cells/cell populations. It’s called the surface sensing of translation, or SUnSET assay. It is a nonradioactive fluorescence-activated assay, which means...

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