1. Daptomycin: Frequently Asked Questions - Answered!

    Daptomycin: Frequently Asked Questions - Answered!
    For the last 15 years, A.G. Scientific has been a leading supplier of Daptomycin. We offer a range of catalog sizes, as well as, multi-kilogram quantities for bulk applications. Additionally, we provide a full service of bottling, sterile formulations, custom packaging, as well as, comprehensive private labeling capabilities.
  2. Beta-Lactamase and Microbial Antibiotic Resistance

    Beta-Lactamase and Microbial Antibiotic Resistance
    β-Lactamases continue to be the leading cause of resistance to β-lactam antibiotics among gram-negative bacteria. In recent years there has been an increased incidence and prevalence of extended-spectrum β-lactamases (ESBLs), enzymes that hydrolyze and cause resistance to oxyimino-cephalosporins and aztreonam.
  3. G418 Sulfate (Geneticin): Protocols and FAQs

    G418 Sulfate (Geneticin): Protocols and FAQs
    or the last 18 years, AG Scientific has been a leading manufacturer, retail supplier and wholesaler of g-418, Geneticin®. Our success with a combination of fermentation & synthesis that has allowed us to build a catalog of over 180 antibiotics and a customer base of researchers, catalog biochemical distributors and cell media manufacturers worldwide.
  4. Ionophores: Ion Carriers and Channels for Membrane Transport

    Ionophores: Ion Carriers and Channels for Membrane Transport
    Ionophores are molecules that facilitate ion passage in or out of cell membranes. Ion carrier: A substance that can transfer ions from a hydrophilic medium, such as water, into a hydrophobic medium, i.e a biological membrane, where the ions typically would not be soluble.
  5. Valinomycin Ionophore: Frequently Asked Questions

    Valinomycin Ionophore: Frequently Asked Questions
    Valinomycin is a potent antibiotic which acts as a potassium (K+) ionophore. Induces K+ conductivity in cell membranes. Also active in vitro against Mycobacterium Tuberculosis, and as an apoptosis inducer. Valinomycin is obtained from the cells of several Streptomyces strains, among which "S. tsusimaensis" and S. fulvissimus.
  6. Blasticidin S Hydrochloride: Frequently Asked Questions

    Blasticidin S Hydrochloride: Frequently Asked Questions
    Blasticidin S is an antibiotic used by scientists in bio-research to select cells modified by genetic engineering. It inhibits the growth of a wide range of prokaryotic and eukaryotic cells by interfering with protein synthesis. Blasticidin S allows the selection and maintenance of cells expressing the blasticidin-resistance gene.
  7. Hygromycin B: Most Frequently Asked Questions

    Hygromycin B: Most Frequently Asked Questions
    A.G.Scientific emerged as a leading manufacturer and importer of Hygromycin B, an antibiotic used for gene selection. Over the past 18 years we have learned a lot about this Aminoglycosides antibiotic. It was our success with a combination of fermentation & synthesis that has allowed us to build a customer base of researchers and catalog biochemical distributors worldwide. Questions on solution storage & what are the procedures to determine toxic concentration are common to all customers of Hygromycin. So here we listed the top questions we have received from our customers.
  8. Rapamycin: Most Commonly Asked Questions

    Rapamycin: Most Commonly Asked Questions
    Discovery of Rapamycin Rapamycin is a macrocyclic triene antibiotic that binds to the cytosolic protein FK-binding protein 12 (FKBP12) and inhibits mTOR pathway by directly binding to the mTOR Complex 1 (mTORC1). It is a potent immunosuppressant having a variety of uses both in vitro and in vivo and is used to prevent organ rejection after transplantation. Chemical structure of...
  9. A23187: Uncouples Oxidative Phosphorylation and Inhibits ATPase

    A23187: Uncouples Oxidative Phosphorylation and Inhibits ATPase Chemical structure of calcium ionophore A23187 A23187 is a carboxylic acid antibiotic which simultaneously uncouples oxidative phosphorylation and inhibits ATPase of rat liver mitochondria incubated in a magnesium-free medium. The antibiotic acts as a freely mobile carrier to transport calcium and magnesium, but not potassium, from an aqueous medium buffered at pH 7.4...
  10. 9 Tips Influencing Successful Puromycin Gene Transfection

    9 Tips Influencing Successful Puromycin Gene Transfection
    Puromycin is an aminonucleosidic antibiotic. Puromycin is a protein synthesis inhibitor by inhibiting translation. Puromycin’s main function is used in cell biology as a selective antibiotic agent in cell culture systems.

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