1. Popular Anti-Fungal Drugs: An Overview

    Popular Anti-Fungal Drugs: An Overview
    Anti-fungal drugs play an important role in treating serious medical conditions. These drugs are used to treat primary fungal infections as well as secondary infections. Anti-fungal drugs can be administered through different channels and play a key role in keeping cancer patients and organ donors healthy. Let's examine how these drugs work and why continued research and development is so...
  2. Using Bicyclomycin to Treat Drug-Resistant Bacterial Infections

    Using Bicyclomycin to Treat Drug-Resistant Bacterial Infections
    Stating that antibiotics, first discovered in 1928 and commercially used by the 1940s, brought an unprecedented change to the world is not an overstatement. For decades now we have routinely cured illnesses and infections that were previously life-threatening. In recent years, however, bacterial infections have increasingly grown resistant to antibiotics. According to the CDC, approximately 2.8 million people each year...
  3. The SUnSET Assay: Powerful Proteomics

    The SUnSET Assay: Powerful Proteomics
    The SUnSET Assay: Powerful Proteomics Exciting advances in the study of protein synthesis and related health conditions are on the horizon! Research scientists have developed an improved process to quantify and understand the processes of protein synthesis in singular eukaryotic cells/cell populations. It’s called the surface sensing of translation, or SUnSET assay. It is a nonradioactive fluorescence-activated assay, which means...
  4. Amphotericin B for Viral Disease Research

    Amphotericin B for Viral Disease Research
    Amphotericin B for Viral Disease Research Amphotericin B is an antibiotic that has been used for over fifty years as an aggressive and effective antifungal treatment.  It battles serious fungal infections like cryptococcal meningitis with ease.  Often called by its brand name, Fungizone, this antibiotic is effective in saving lives and has been relied upon for decades because pathogens have...
  5. Pathology Research Using Mitophagy Modulators

    Pathology Research Using Mitophagy Modulators
    Pathology Research Using Mitophagy Modulators When you hear “small things with big impact”, do you immediately think of mitochondria and mitophagy modulators? Probably not! But these little organelles are champions of cell regulation.  Among their functions is regulating the energy of the cell as well as cell death. And just as mitochondria are responsible for cell function, mitophagy is responsible...
  6. Hydroxychloroquine: Misconceptions in the Media

    Hydroxychloroquine: Misconceptions in the Media
    Hydroxychloroquine: Misconceptions in the Media It’s hard to miss hearing the word “hydroxychloroquine” being associated with coronavirus in the news right now.  Hydroxychloroquine is being touted as a “game changer” in treating coronavirus by people in the current US administration who are not medical professionals. This drug has a similar structure to a previously established drug called CQ (N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine), which...
  7. Tunicamycin: ER Stress Inducer

    Tunicamycin: ER Stress Inducer
    Tunicamycin: ER Stress Inducer When we hear the terms cell death and endoplasmic reticulum (ER) stress, what first comes to mind?  3D illustration of protein folding Stress? Death? Two concepts that don’t exactly inspire positive thoughts.  However, in the case of the antibiotic compound tunicamycin, cell death and ER stress are the objectives.  What is Tunicamycin? Tunicamycin is an antibiotic...
  8. Daptomycin: Frequently Asked Questions - Answered!

    Daptomycin: Frequently Asked Questions - Answered!
    For the last 15 years, A.G. Scientific has been a leading supplier of Daptomycin. We offer a range of catalog sizes, as well as, multi-kilogram quantities for bulk applications. Additionally, we provide a full service of bottling, sterile formulations, custom packaging, as well as, comprehensive private labeling capabilities.
  9. Beta-Lactamase and Microbial Antibiotic Resistance

    Beta-Lactamase and Microbial Antibiotic Resistance
    β-Lactamases continue to be the leading cause of resistance to β-lactam antibiotics among gram-negative bacteria. In recent years there has been an increased incidence and prevalence of extended-spectrum β-lactamases (ESBLs), enzymes that hydrolyze and cause resistance to oxyimino-cephalosporins and aztreonam.
  10. G418 Sulfate (Geneticin): Protocols and FAQs

    G418 Sulfate (Geneticin): Protocols and FAQs
    or the last 18 years, AG Scientific has been a leading manufacturer, retail supplier and wholesaler of g-418, Geneticin®. Our success with a combination of fermentation & synthesis that has allowed us to build a catalog of over 180 antibiotics and a customer base of researchers, catalog biochemical distributors and cell media manufacturers worldwide.

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