1. Ion-Selective Electrodes (ISE): An Introduction

    Ion-Selective Electrodes (ISE): An Introduction
    Ion-Selective Electrodes (ISE): An Introduction Ion-selective electrodes have a wide variety of industrial and research uses. They offer a comprehensive method in testing the level of activity of ions contained within aqueous solutions. This is a necessary process to determine the electrical potential (conductivity) of a substance or solution, through potentiometry. What Are Ion-selective Electrodes? Ion-selective electrodes are also known...
  2. Decoding Chemical Grades For Your Lab

    Decoding Chemical Grades For Your Lab
    Decoding Chemical Grades For Your Lab Handling chemicals is serious business. In order for researchers to create the solution they need for an experiment, they have to choose reagents of the right chemical grades. Choosing an insufficient grade could have unanticipated affects when added to a system. When a chemical reagent is graded by its manufacturer, customers are able to...
  3. 5 Things to Consider When Choosing Biological Buffers

    5 Things to Consider When Choosing Biological Buffers
    5 Things to Consider When Choosing Biological Buffers According to ThoughtCo., biological buffers usually consist of a conjugate base and a weak acid or a conjugate acid and weak base. A buffer is a type of solution that helps maintain stable pH levels. Successful research is dependent on finding and using the right buffer. The following are five important aspects...
  4. Daptomycin: Frequently Asked Questions - Answered!

    Daptomycin: Frequently Asked Questions - Answered!
    For the last 15 years, A.G. Scientific has been a leading supplier of Daptomycin. We offer a range of catalog sizes, as well as, multi-kilogram quantities for bulk applications. Additionally, we provide a full service of bottling, sterile formulations, custom packaging, as well as, comprehensive private labeling capabilities.
  5. Bestatin (Ubenimex): Applications in Life Science Research

    Bestatin (Ubenimex): Applications in Life Science Research
    Bestatin, also known as Ubenimex, is a competitive protease inhibitor. It is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. It is being studied for use in the treatment of acute myelocytic leukemia.
  6. Beta-Lactamase and Microbial Antibiotic Resistance

    Beta-Lactamase and Microbial Antibiotic Resistance
    β-Lactamases continue to be the leading cause of resistance to β-lactam antibiotics among gram-negative bacteria. In recent years there has been an increased incidence and prevalence of extended-spectrum β-lactamases (ESBLs), enzymes that hydrolyze and cause resistance to oxyimino-cephalosporins and aztreonam.
  7. Differences Between Necrosis and Necroptosis

    Differences Between Necrosis and Necroptosis
    Cell death has traditionally been subdivided into regulated (apoptosis) and unregulated (necrosis) forms. While apoptosis has always been recognized to be a pathway of highly orchestrated signaling events, necrosis or necrotic cell death is known as a fortuitous and unregulated means of cell death that is induced by nonspecific and nonphysiological stress.
  8. What is Thapsigargin? Frequently Asked Questions

    What is Thapsigargin? Frequently Asked Questions
    Thapsigargin is derived from the plant Thapsia garganica that produces tumor promoters. This effect is a result of emptying the intracellular calcium stores, which leads to a chain of events that causes apoptosis. Mechanism of Action Chemical structure of Thapsigargin Thapsigargin is an inhibitor of sarco endoplasmic reticulum Ca2 ATPase (SERCA). It pumps calcium ions from the cytoplasm into the lumen...
  9. CHAPS Detergent: Protocols and Frequently Asked Questions

    CHAPS Detergent: Protocols and Frequently Asked Questions
    A nondenaturing zwitterionic detergent for solubilizing membrane proteins and breaking protein-protein interactions. Combines the useful properties of both the sulfobetaine-type and the bile salt detergents. Commonly used for protein solubilization in isoelectric focusing and two-dimensional electrophoresis especially for non-denaturing (without urea) isoelectric focusing.
  10. RNase A: Frequently Asked Questions

    RNase A: Frequently Asked Questions
    Introduction to RNase Ribonucleases (RNases) are a large group of hydrolytic enzymes that degrade ribonucleic acid (RNA) molecules. These are nucleases that catalyze the breakdown of RNA into smaller components. They are a superfamily of enzymes which catalyze the degradation of RNA, operating at the levels of transcription and translation. 3D conformation of ribonuclease A enzyme These enzymes are present...

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