Understanding PMSF PMSF (phenylmethylsulfonyl fluoride) is an irreversible serine protease inhibitor used in various research and lab settings. The compound has a white powdery appearance at room temperature, with a melting point between 90-95°C. It functions by inhibiting serine proteases such as trypsin, chymotrypsin, and thrombin, and cysteine proteases like papain. The process involves the deactivation of enzymes that contain...

A trend in modern scientific research over the past decade is using smaller & smaller methods of studying targets, like molecules. Independent, smaller devices, and less expensive methods allow more access for researchers across the board, regardless of their space and budget. One such analytical method is the creation of artificial nanopore sensors for research using nanopore electrochemistry. Capturing reactions...

Amphotericin B for Viral Disease Research Amphotericin B is an antibiotic that has been used for over fifty years as an aggressive and effective antifungal treatment.  It battles serious fungal infections like cryptococcal meningitis with ease.  Often called by its brand name, Fungizone, this antibiotic is effective in saving lives and has been relied upon for decades because pathogens have...

Guanidine Thiocyanate in RNA Lysis Buffers and COVID-19 Research Guanidine thiocyanate chemical structure With COVID-19 ever present on our minds, viral research is being focused on now more than anything else. We at AG Scientific have remained open to meet the needs of the research community and are stocking chemical agents such as guanidine thiocyanate.  Read on to learn more...

Ruthenium: Applications in Medical & Energy Technologies Ruthenium is used as a catalyst, in addition to being one of the rarest metals on the planet. It speeds up chemical processes with precision and aides in electrochemical energy technologies as well as renewable energy conversions. It is mainly found with platinum in small amounts around the world, and for being so...

Tips for Selecting Biological Detergents Biological detergents are chemicals classified as surfactants, or surface-active molecules. Research scientists typically use these detergents in affecting the interactions within molecules of a biological sample being studied. These surfactants are used in biochemical research to target and manipulate the structure of membrane proteins without sacrificing their integrity or impacting their original function. Membrane proteins...

EDAC HCl Reducing Agent: Frequently Asked Questions AG Scientific is a leading supplier of EDAC HCl. Here we review some of the most frequently asked questions about this useful reducing agent: 1. What is EDAC HCl? EDAC Hydrochloride is a versatile modern reducing agent. It is an easily handled solid with high solubility in water and organic solvents such as dichloromethane...

TCEP Reducing Agent: Frequently Asked Questions AG Scientific is a leading supplier of TCEP HCl. Here we review some of the most frequently asked questions about this useful reducing agent: What is TCEP? This is a useful reducing agent with applications in molecular biology, biochemistry and microbiology Are there alternative names for this product? TCEP hydrochloride Tris(2-carboxyethyl)phosphine hydrochloride   Fig 1...

DTE Reducing Agent: Frequently Asked Questions AG Scientific is a leading supplier of DTE reducing agent. Here we review some of the most frequently asked questions about this useful chemical: What is DTE? DTE (formally 1,4-Dithioerythritol) is an epimer of DTT (dithiothreitol). This sugar is derived from the corresponding 4-carbon monosaccharide erythrose and contains sulfur. It is an epimer of...

5 Things to Consider When Choosing Biological Buffers According to ThoughtCo., biological buffers usually consist of a conjugate base and a weak acid or a conjugate acid and weak base. A buffer is a type of solution that helps maintain stable pH levels. Successful research is dependent on finding and using the right buffer. The following are five important aspects...