1. Cibacron Blue Applications

    Cibacron Blue Applications
    Cibacron Blue 3GA is a textile dye or ligand frequently used as a medium for affinity chromatography experiments, specifically for the purification of enzymes. The ligand appears as a blue powder under room temperature settings. Scientists and researchers commonly choose the compound for its affordability, ease of immobilization, high resistance against biological and chemical degradation, and high protein-binding capacity of...
  2. Avoiding Cross-Contamination in Antibiotic Manufacturing

    Avoiding Cross-Contamination in Antibiotic Manufacturing
    There are two major categories of antibiotics: penicillin beta-lactam and non-penicillin beta-lactam products. Research authorities have identified five primary groups under the beta-lactam category of antibiotics, including penicillins, cephalosporins, penems, carbacephems, and monobactams. Avoiding cross-contamination between penicillin and non-penicillin products remains a top concern for drug manufacturers despite the modern day success of antibiotics. Penicillin is an umbrella term for...
  3. In Vitro Mutagenesis for Genetic Research

    In Vitro Mutagenesis for Genetic Research
    Scientists and researchers turn to cloned DNA for various breakthrough studies as they provide multiple genetic copies and DNA segments suitable for wide-scale tests. In vitro mutagenesis is one useful application of cloned DNA, where researchers create a mutation in one segment of the target DNA. The cloned DNA is then transferred into a cell or organism and studied, which provides...
  4. Water Quality and Dairy Quality Testing FAQs

    Water Quality and Dairy Quality Testing FAQs
    Whenever you pour yourself a glass of water, it may appear to be clean and you might expect the water quality to be safe. However, many sources of water contain dissolved minerals, organic compounds, or live pathogens at harmful levels. Other minerals in your water could also result in an unpleasant taste, odors, and could stain bathroom fixtures or your...
  5. Sources of DNA Contamination in the Laboratory

    Sources of DNA Contamination in the Laboratory
    The polymerase chain reaction (PCR) technique, used to amplify or “copy” small segments of DNA, is highly sensitive - and that’s a good thing. PCR is a widely used and inexpensive technique used in medical diagnostics, forensic analysis of DNA, and genomic research. Unfortunately, this sensitivity leaves PCR vulnerable to nucleic acid contamination: even trace amounts of DNA can be...
  6. 7 Sources of Antibiotic Resistance

    7 Sources of Antibiotic Resistance
    The growing increase of antibiotic resistance is now a global problem. According to the National Foundation for Infectious Disease, approximately 3 million people each year struggle with infections from antibiotic resistant bacteria. About 35,000 individuals will die as a result of these infections. Antibiotic resistance is a concern for several important reasons. Illnesses such as strep throat, tuberculosis, and certain...
  7. Popular Anti-Fungal Drugs: An Overview

    Popular Anti-Fungal Drugs: An Overview
    Anti-fungal drugs play an important role in treating serious medical conditions. These drugs are used to treat primary fungal infections as well as secondary infections. Anti-fungal drugs can be administered through different channels and play a key role in keeping cancer patients and organ donors healthy. Let's examine how these drugs work and why continued research and development is so...
  8. Sequencing Batch Reactors (SBR) for Wastewater Treatment

    Sequencing Batch Reactors (SBR) for Wastewater Treatment
    Sequencing batch reactors (SBRs), also known as sequential batch reactors, are activated sludge systems applied in wastewater treatment. SBR systems are upgrades of conventional activated sludge systems that minimize footprint by integrating separate functions in a single treatment system. Standard SBR setups usually include the reactor basin, water sludge draw-off mechanism, effluent decanter, and process control system. How Do Sequencing...
  9. PMSF: Serine Protease Inhibitor Applications

    PMSF: Serine Protease Inhibitor Applications
    Understanding PMSF PMSF (phenylmethylsulfonyl fluoride) is an irreversible serine protease inhibitor used in various research and lab settings. The compound has a white powdery appearance at room temperature, with a melting point between 90-95°C. It functions by inhibiting serine proteases such as trypsin, chymotrypsin, and thrombin, and cysteine proteases like papain. The process involves the deactivation of enzymes that contain...
  10. Nanopore Electrochemistry: Single-Molecule Sensors

    Nanopore Electrochemistry: Single-Molecule Sensors
    A trend in modern scientific research over the past decade is using smaller & smaller methods of studying targets, like molecules. Independent, smaller devices, and less expensive methods allow more access for researchers across the board, regardless of their space and budget. One such analytical method is the creation of artificial nanopore sensors for research using nanopore electrochemistry. Capturing reactions...

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