1. 5 Things to Consider When Choosing Biological Buffers

    5 Things to Consider When Choosing Biological Buffers
    5 Things to Consider When Choosing Biological Buffers According to ThoughtCo., biological buffers usually consist of a conjugate base and a weak acid or a conjugate acid and weak base. A buffer is a type of solution that helps maintain stable pH levels. Successful research is dependent on finding and using the right buffer. The following are five important aspects...
  2. Calcium Ionophore I: Frequently Asked Questions

    Calcium Ionophore I: Frequently Asked Questions
    Calcium Ionophore I: Frequently Asked Questions AG Scientific is a leading supplier of Calcium Ionophore I (CA 1001). Here we review some of the most frequently asked questions about this powerful ionophore. What is Calcium Ionophore I? Calcium Ionophore I (CA 1001) is a neutral ionophore with very high selectivity for Ca2+ ions. CA 1001 determines Ca2+ activity in membrane...
  3. Daptomycin: Frequently Asked Questions - Answered!

    Daptomycin: Frequently Asked Questions - Answered!
    For the last 15 years, A.G. Scientific has been a leading supplier of Daptomycin. We offer a range of catalog sizes, as well as, multi-kilogram quantities for bulk applications. Additionally, we provide a full service of bottling, sterile formulations, custom packaging, as well as, comprehensive private labeling capabilities.
  4. Bestatin (Ubenimex): Applications in Life Science Research

    Bestatin (Ubenimex): Applications in Life Science Research
    Bestatin, also known as Ubenimex, is a competitive protease inhibitor. It is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. It is being studied for use in the treatment of acute myelocytic leukemia.
  5. Beta-Lactamase and Microbial Antibiotic Resistance

    Beta-Lactamase and Microbial Antibiotic Resistance
    β-Lactamases continue to be the leading cause of resistance to β-lactam antibiotics among gram-negative bacteria. In recent years there has been an increased incidence and prevalence of extended-spectrum β-lactamases (ESBLs), enzymes that hydrolyze and cause resistance to oxyimino-cephalosporins and aztreonam.
  6. IPTG: Frequently Asked Questions and Protocols

    IPTG: Frequently Asked Questions and Protocols
    IPTG is a molecular biology reagent utilized in cloning experiments. This compound is used as a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lacoperon. Unlike allolactose, the IPTG sulfur (S) atom creates a chemical bond which is non-hydrolyzable by the cell, preventing the cell from "eating up" or degrading the inductant; therefore the IPTG concentration remains constant.
  7. PMSF Inhibitor: Frequently Asked Questions

    PMSF Inhibitor: Frequently Asked Questions
    About PMSF Inhibitor An important serine protease inhibitor commonly utilized by biochemists and researchers, phenylmethylsulfonyl fluoride (PMSF) is often used to prepare cell lysates, helping to preserve critical samples. Acting as a non-specific inhibitor, PMSF is often used to protect samples against the digestive functions of proteases, such as trypsin, chymotrypsin, and thrombin, as well as other enzymes. It is...
  8. G418 Sulfate (Geneticin): Protocols and FAQs

    G418 Sulfate (Geneticin): Protocols and FAQs
    or the last 18 years, AG Scientific has been a leading manufacturer, retail supplier and wholesaler of g-418, Geneticin®. Our success with a combination of fermentation & synthesis that has allowed us to build a catalog of over 180 antibiotics and a customer base of researchers, catalog biochemical distributors and cell media manufacturers worldwide.
  9. Ionophores: Ion Carriers and Channels for Membrane Transport

    Ionophores: Ion Carriers and Channels for Membrane Transport
    Ionophores are molecules that facilitate ion passage in or out of cell membranes. Ion carrier: A substance that can transfer ions from a hydrophilic medium, such as water, into a hydrophobic medium, i.e a biological membrane, where the ions typically would not be soluble.
  10. Differences Between Necrosis and Necroptosis

    Differences Between Necrosis and Necroptosis
    Cell death has traditionally been subdivided into regulated (apoptosis) and unregulated (necrosis) forms. While apoptosis has always been recognized to be a pathway of highly orchestrated signaling events, necrosis or necrotic cell death is known as a fortuitous and unregulated means of cell death that is induced by nonspecific and nonphysiological stress.

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