1. TCEP HCl vs DTT: Preferred Reducing Agents

    TCEP HCl vs DTT: Preferred Reducing Agents
    TCEP. HCl has the advantages of being odorless, a more powerful reducing agent, an irreversible reducing agent, more hydrophilic, and more resistant to oxidation in air. Near complete reduction of disulfide bonds. DTT is a protective agent for reducing –S-S TO SH groups. Used as a strong reducing agent for proteins and enzymes.
  2. Proteinase K - Bulk Packaging & Labeling Services

    Proteinase K - Bulk Packaging & Labeling Services
    AG Scientific is the established leader in Proteinase K bulk supply, catalog packaging, custom size vialing and private labeling services. We guarantee the following:
  3. 20 FACTS ABOUT PROTEASOMES & PROTEASOME INHIBITORS!

    1. Proteasome inhibitors are drugs that block the action of proteasomes, cellular complexes that break down proteins, like the p53 protein. Proteasome inhibitors are being studied in the treatment of cancer, especially multiple myeloma.
  4. DTT (Dithiothreitol): Frequently Asked Questions

    For the last 18 years, AG Scientific has been a leading supplier of DTT, dithiothreitol, historically known as Cleland’s Reagent. We offer a range of catalog sizes, as well as, multi-kilogram quantities for bulk applications. Additionally, we provide a full service of bottling, sterile formulations, custom packaging, as well as, comprehensive private labeling capabilities.
  5. Cancer Treated by Purifying Proteins

    Cancer Treated by Purifying Proteins Protein purification is a series of processes intended to isolate a single type of protein from a complex mixture. Protein purification is vital for the characterization of the function, structure and interactions of the protein of interest. The starting material is usually a biological tissue or a microbial culture. The various steps in the purification...
  6. How to Use Proteases for Protein Proteolysis

    How to Use Protease/s for Protein Proteolysis Protein Proteolysis refers to the use of hydrochloric acid to destroy peptide bonds between the amino acids that make up a protein. When carried out with proteases (also known as proteinases), which are enzymes, the process is termed proteolysis. Depending on how efficient the enzyme is or what links it breaks, the proteolysis can be limited or unlimited. Proteolysis can begin either from one end of the chain of amino acids that comprise the protein or somewhere in the middle of it. Unlimited proteolysis produces individual amino acids while limited proteolysis produces short chains of polypeptides.
  7. Non-Ionic Protein Solubilizers (Non-Ionic Detergents)

    Non-ionic detergents contain uncharged, hydrophilic head groups that consist of eithermicelle polyoxyethylene moieties as in TWEEN and TRITON or glycosidic groups as in octyl glucoside and dodecyl maltoside. In general, non-ionic detergents are better suited for breaking lipid-lipid and lipid-protein interactions than protein-protein interactions.
  8. Phosphatase Inhibitor Cocktails, Ready Made Formulations

    Invasive phosphatases can contaminate research samples and slow or halt research progress, rendering time-consuming and expensive work useless.

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