• Collagenase Enzymes: History, Applications, and Mechanisms of Action 2019-02-21 09:49:35 Since their initial discovery in the 1950s, collagenase enzymes now play a key role in modern scientific research. They have also been approved for therapeutic use when aiming to treat Peyronie’s disease and Dupuytren’s, and also actively support wound healing.   There are various c Test tube rack
  • Polyene Macrolide Antibiotics 2018-12-26 13:31:12 It has been 60 years since the first report of erythromycin in 1952. Over the course of this 60 years the macrolide antibiotics—14- and 16-membered macrolactams—have been followed at intervals by the lincosamides, streptogramins, azalides and now the ketolides.
  • Anthracyclines: Anti-Cancer Compounds 2018-12-03 09:00:57 Anthracyclines are anticancer compounds that were originally derived from Streptomyces and their anti-tumor activitieswere established in the 1960s. Anthracyclines are red aromatic polyketides and occur in variety of forms due to the structural differences in the aglycone and the different sugar res Beaker and pipette
  • The Ultimate Guide to Beta Lactamase 2018-11-20 11:30:59 Beta Lactamase Mechanism Beta lactam antibiotics, like cephams and penicillin derivatives, have a four-member cyclic amide ring that inhibits the peptidoglycan layer synthesis in bacteria. A woven complex of sugar and protein pieces, these first-class bactericidal drugs destroy the integrity of
  • Penicillin: How We Made a Global Savior 2018-11-19 11:00:24 The name 'antibiotic' was first given to the drugs that exhibit 'antibiosis' (meaning 'against life'), by Selman Waksman in 1942. After Vincenzo Tiberio discovered a mold (penicillium) in a well that displayed antibacterial, it led others to find the reasoning behind this. However, it was Alexander Cell culture agar plate
  • How Safe Is Your Water? 2018-11-15 11:00:32   Water Contamination The common causes of acute diarrhea are viruses and bacteria. Diarrhea is a symptom of infections caused by a host of bacterial, viral and parasitic organisms, most of which are spread by feces-contaminated water. Escherichia coli (E. coli) are a large and diverse group of Water splashing
  • Water Quality and Dairy Quality Testing – FAQs 2018-11-14 09:30:33 Whenever you pour yourself a glass of water, it may appear to be clean and you might expect the water quality to be safe. However, many sources of water contain dissolved minerals, organic compounds, or live pathogens at harmful levels. Other minerals in your water could also result in an unpleasant Water Testing
  • 17 Need to Know Facts About RNase A 2018-11-13 09:00:36 Introduction to RNase Ribonucleases (RNases) are a large group of hydrolytic enzymes that degrade ribonucleic acid (RNA) molecules. RNases are nucleases that catalyze the breakdown of RNA into smaller components. RNases are a superfamily of enzymes which catalyze the degradation of RNA, operating at
  • Proteinase K Applications in Prion-Related Diseases 2018-11-10 11:01:49 Proteinase K degrades almost every protein and inactivates rapidly enzymatic activities under a broad range of conditions (SDS, Urea, pH 4 -12). The enzyme is used for the isolation of clean and native genomic DNA and RNA in order to guarantee PCR based detection. prions, prion, proteinase k
  • Beta-Lactamase Hybrid Proteins 2018-11-06 12:38:35 Introduction Beta-lactam antibiotics are used to treat a broad spectrum of Gram-positive and Gram-negative bacteria.   β-lactam antibiotics target the penicillin-binding proteins (PBPs) – a group of enzymes found attached in the cell membrane, which are involved in the cross-linking Beta Lactam Antibiotics