• Polyene Macrolide Antibiotics 2018-12-26 13:31:12 It has been 60 years since the first report of erythromycin in 1952. Over the course of this 60 years the macrolide antibiotics—14- and 16-membered macrolactams—have been followed at intervals by the lincosamides, streptogramins, azalides and now the ketolides.
  • The Ultimate Guide to Beta Lactamase 2018-11-20 11:30:59 Beta Lactamase Mechanism Beta lactam antibiotics, like cephams and penicillin derivatives, have a four-member cyclic amide ring that inhibits the peptidoglycan layer synthesis in bacteria. A woven complex of sugar and protein pieces, these first-class bactericidal drugs destroy the integrity of
  • How Safe Is Your Water? 2018-11-15 11:00:32   Water Contamination The common causes of acute diarrhea are viruses and bacteria. Diarrhea is a symptom of infections caused by a host of bacterial, viral and parasitic organisms, most of which are spread by feces-contaminated water. Escherichia coli (E. coli) are a large and diverse group of Water splashing
  • Beta-Lactamase Hybrid Proteins 2018-11-06 12:38:35 Introduction Beta-lactam antibiotics are used to treat a broad spectrum of Gram-positive and Gram-negative bacteria.   β-lactam antibiotics target the penicillin-binding proteins (PBPs) – a group of enzymes found attached in the cell membrane, which are involved in the cross-linking Beta Lactam Antibiotics
  • Carbenicillin Antibiotic – Top 7 FAQs 2018-11-06 02:00:05 Using carbenicillin antibiotics in your research? Get to know these top frequently asked questions! 1. What is Carbenicillin? Carbenicillin, also known as carboxybenzylpenicillin, is a member of the penicillin β-lactam antibiotics. Unlike most β-lactams, carbenicillin disodium is limi
  • Antibiotics at AG Scientific 2018-10-31 11:42:20 One of our most popular antibiotics, anisomycin, is a protein and DNA synthesis inhibitor that specializes in inhibiting the 80S ribosome network (eukaryotes). Anisomycin’s properties of inhibition become activated when concentrations are enough to effect greater than 95% of the 80S ribosome DNA Assay
  • Neomycin Applications 2017-09-25 08:20:52 Neomycins are a family of broad-spectrum highly toxic antibiotics produced by Streptomyces fradiae. Neomycin usually exists as a complex composed of two stereoisomers, neomycin B and neomycin C, which are the two active components. A third component,&A
  • Nonactin based biosensors to measure ammonia 2017-09-25 08:18:33 Ammonia (NH3) is a poisonous and pungent-smelling colorless gas that makes the eyes water. Ammonia is readily soluble in water. The aqueous solution has an alkaline reaction and is known as ammonia water or tincture of ammonia. In conjunction with acid, ammonia forms salts that disassociate in water
  • 18 Facts about Rapamycin 2017-03-14 11:56:06 Discovery of Rapamycin Rapamycin is a macrocyclic triene antibiotic that binds to the cytosolic protein FK-binding protein 12 (FKBP12) and inhibits mTOR pathway by directly binding to the mTOR Complex1 (mTORC1). It is a potent immunosuppressant having  a variety of uses both in vitro and
  • Beta Lactamase Inhibitors in Research: Anti-Seizure 2016-10-24 16:00:22 Beta-lactam antibiotics contain a cyclic amide ring of which mimics the structure of the terminal amino acid residues comprising the peptidoglycan matrix. It is this structure that the enzyme beta lactamase acts upon as a method of antibiotic defense, hydrolyzing the ring and compromising the struct