• Beta-Lactamase Hybrid Proteins 2018-11-06 12:38:35 Introduction Beta-lactam antibiotics are used to treat a broad spectrum of Gram-positive and Gram-negative bacteria.   β-lactam antibiotics target the penicillin-binding proteins (PBPs) – a group of enzymes found attached in the cell membrane, which are involved in the cross-linking Beta Lactam Antibiotics
  • Carbenicillin Antibiotic – Top 7 FAQs 2018-11-06 02:00:05 Using carbenicillin antibiotics in your research? Get to know these top frequently asked questions! 1. What is Carbenicillin? Carbenicillin, also known as carboxybenzylpenicillin, is a member of the penicillin β-lactam antibiotics. Unlike most β-lactams, carbenicillin disodium is limi
  • Protease Enzymes – Common Applications 2018-11-06 01:00:19 Introduction to Protease Enzymes There are five families of proteases in which serine (eg: proteinase K/protease K/endopeptidase K), threonine, cysteine, aspartic or metallic groups play a primary catalytic role. Protease enzymes break the long chain-like molecules of proteins into shorter fragments
  • Part 2: Solving Mysteries with Trypsin and Proteinase K 2018-11-05 17:17:39 In Part 1, we discussed using trypsin on bone specimens as a cleaning alternative to sanding in preparation for DNA extraction. In this second part of the series, we cover the details of attaining a higher yield of DNA using proteinase K. Proteinase K for Higher DNA Yield from Bone Specimens DN Proteinase K
  • Part 1: Solving Mysteries with Trypsin and Proteinase K 2018-11-04 23:10:39 Identifying Human Remains Human remains are fascinating. They have many properties that can be used to identify a person: distinct scars, special features, dental x-rays, fingerprint comparisons, or physical facial characteristics. Forensic scientists attempt to identify human skeletal remains in si
  • Puromycin – Anti-Tumor Effect and Activity 2018-11-01 01:00:44 Puromycin is an aminonucleoside antibiotic produced by the bacterium Streptomyces alboniger. It inhibits protein synthesis by disrupting peptide transfer on ribosomes causing premature chain termination during translation. Photo by Louis Reed on Unsplash
  • Antibiotics at AG Scientific 2018-10-31 11:42:20 One of our most popular antibiotics, anisomycin, is a protein and DNA synthesis inhibitor that specializes in inhibiting the 80S ribosome network (eukaryotes). Anisomycin’s properties of inhibition become activated when concentrations are enough to effect greater than 95% of the 80S ribosome DNA Assay
  • RNase A Brochure – AG Scientific 2018-10-17 11:41:40 Learn more about RNase A.
  • CK-666: Inhibitor of Actin-Related Proteins 2018-06-27 11:16:13 Actin is a family of globular multi-functional proteins that form microfilaments. Microfilaments, also called actin filaments, are filaments in the cytoplasm of eukaryotic cells that form part of the cytoskeleton. Actin participates in many important cellular processes, including muscle contraction,
  • SMER28- Enhancer of Autophagy 2018-06-13 11:07:20 SMER28 is a small-molecule enhancer (SMER) of autophagy that increases autophagosome synthesis and enhances clearance of aggregate-prone substrates, including those relevant to Huntington’s, Parkinson’s, and Alzheimer’s diseases.   It is a positive regulator of autophagy in a