1. Anthracyclines: Anti-Cancer Compounds

    Anthracyclines: Anti-Cancer Compounds
    Anthracyclines are anticancer compounds that were originally derived from Streptomyces and their anti-tumor activitieswere established in the 1960s. Anthracyclines are red aromatic polyketides and occur in variety of forms due to the structural differences in the aglycone and the different sugar residues attached.
  2. Doxorubicin in Cancer Chemotherapy

    Doxorubicin; trade name Adriamycin; also known as hydroxydaunorubicin, is a drug used in cancer chemotherapy. It is an anthracycline antibiotic, closely related to the natural product daunomycin, and like all anthracyclines, it works by intercalating DNA, while most serious adverse effect being life-threatening heart damage.

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