• Anthracyclines: Anti-Cancer Compounds 2018-12-03 09:00:57 Anthracyclines are anticancer compounds that were originally derived from Streptomyces and their anti-tumor activitieswere established in the 1960s. Anthracyclines are red aromatic polyketides and occur in variety of forms due to the structural differences in the aglycone and the different sugar res Beaker and pipette
  • Bafilomycin as a Cancer Treatment 2017-07-05 08:48:17 Bafilomycins are a family of toxic macrolide antibiotics isolated from Streptomyces species. AG Scientific offers several high-quality bafilomycin products. Bafilomycins at AG Scientific Product Number Product Name B-1183 Bafilomycin A1 B-1185 Bafilomycin B1 B-1245 Bafilomycin B2 B-2535 Bafilomycin Microscopy
  • Thapsigargin Applications: Glioblastoma Multiforme Studies 2016-12-16 16:02:54 Glioblastoma multiforme is the most aggressive and malignant form of gliomas, a group of tumors arising from glial cells of the brain. Glioblastomas are very difficult to treat due to the diffused nature of the tumor itself. The tumor cells have a distinct invasive feature of spreading and diffusing
  • WHAT IS ROLIPRAM AND HOW IS IT USED TO TREAT DEPRESSION? 2013-05-31 12:00:50 Rolipram is commonly known as a drug used to treat depression. It is in the family of drugs referred to as monoamine oxidase inhibitors (MAOI). It promotes the release of norepinepherine, which in term produces a better mood and an alleviation of depression symptoms. Rolipram is actually a select
  • Paclitaxel – A Mitotic Inhibitor Used in Cancer Chemotherapy 2012-05-03 14:03:00 Paclitaxel, Taxus brevifolia, commonly known as the Pacific yew, is a member of the yew family (Taxaceae). It is a small, slow growing evergreen tree native to the northwestern United States (Wheeler et al., 1992).
  • ENZASTAURIN: FIGHTING MALIGNANT CANCERS 2012-04-16 07:11:01 Enzastaurin is a synthetic bisindolylmaleimide with potential antineoplastic activity. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis.
  • Withaferin A (WA) FAQS 2012-03-30 12:14:47 Withaferin A (WA) is derived from the medical plant Withania somnifera (commonly known as ashwagandha or Indian winter cherry), which has been safely used for centuries in Indian Ayurvedic medicine for treatment of different ailments. Suppresion of angiogenisis, alteration of cytoskeletal architect
  • Chemotin and HIF-1 2012-03-21 07:39:23 Hypoxia-inducible factor-1 (HIF-1) is a transcriptional complex that is activated in response to hypoxia and growth factors. HIF-1 plays a central role in tumor progression, invasion, and metastasis.
  • Resveratrol in grapes contains anti-cancer properties 2012-02-29 10:54:37 The naturally occurring dietary compound, trans-resveratrol (trans-3,4',5-trihydroxystilbene), a natural phytoalexin present in grape skins, red wines, and grape juices, is sold over the counter in the United States as a nutritional supplement.