• The Ultimate Guide to Beta Lactamase 2018-11-20 11:30:59 Beta Lactamase Mechanism Beta lactam antibiotics, like cephams and penicillin derivatives, have a four-member cyclic amide ring that inhibits the peptidoglycan layer synthesis in bacteria. A woven complex of sugar and protein pieces, these first-class bactericidal drugs destroy the integrity of
  • How Safe Is Your Water? 2018-11-15 11:00:32   Water Contamination The common causes of acute diarrhea are viruses and bacteria. Diarrhea is a symptom of infections caused by a host of bacterial, viral and parasitic organisms, most of which are spread by feces-contaminated water. Escherichia coli (E. coli) are a large and diverse group of Water splashing
  • Antibiotics at AG Scientific 2018-10-31 11:42:20 One of our most popular antibiotics, anisomycin, is a protein and DNA synthesis inhibitor that specializes in inhibiting the 80S ribosome network (eukaryotes). Anisomycin’s properties of inhibition become activated when concentrations are enough to effect greater than 95% of the 80S ribosome DNA Assay
  • Bafilomycin as a Cancer Treatment 2017-07-05 08:48:17 Bafilomycins are a family of toxic macrolide antibiotics isolated from Streptomyces species. AG Scientific offers several high-quality bafilomycin products. Bafilomycins at AG Scientific Product Number Product Name B-1183 Bafilomycin A1 B-1185 Bafilomycin B1 B-1245 Bafilomycin B2 B-2535 Bafilomycin Microscopy
  • Beta Lactamase Inhibitors in Research: Anti-Seizure 2016-10-24 16:00:22 Beta-lactam antibiotics contain a cyclic amide ring of which mimics the structure of the terminal amino acid residues comprising the peptidoglycan matrix. It is this structure that the enzyme beta lactamase acts upon as a method of antibiotic defense, hydrolyzing the ring and compromising the struct
  • Tweaking The Immune System Can Help Fight Cancer & Block Angiogenesis 2013-08-06 09:36:39 Cancers that become resistant to an important class of drugs might be made vulnerable by tweaking the immune system, a team led by UCSD researcher Napolene Ferrara has found.
  • Treating Cancer Using Epirubicidin 2012-08-09 09:40:58 MECHANISM OF ACTION: epirubicidin, anthracycline, antibiotics, anticancerThe mechanism of action of epirubicin appears to be related to its ability to bind to nucleic acids. It forms a complex with DNA by intercalation between base pairs, resulting in inhibition of DNA and RNA synthesis. Intercalati
  • MG-132: Fighting Cancer Cells 2012-07-26 12:05:30 Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) is a promising anticancer agent because it induces apoptosis in cancer cells but not in normal cells.
  • OUTSMARTING MRSA BACTERIA 2012-07-25 10:12:28 A 12-year-old boy who was diving for a basketball in his school gym in New York City got a cut on his arm. The incident was nothing out of the ordinary, but bacteria entered Rory Staunton’s bloodstream through the cut; he developed sepsis and died three days later. The New York Times carri
  • Proteasome Inhibitor MG132 Induces Death Receptor 2012-07-20 14:00:32 Combined treatment with a proteasome inhibitor and tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) is a promising strategy for cancer therapy.