UC San Diego researchers say they've found an immune system molecule that directly kills chronic lymphocytic leukemia cells without harming healthy ones. The molecule, called a monoclonal antibody, is being readied for human clinical trials in the not-too-distant future, lead researcher Thomas J. Kipps said. Kipps holds the Evelyn and Edwin Tasch Chair in Cancer Research at the UCSD Moores...
Apoptosis, or cell suicide, is a form of cell death that is morphologically and biochemically distinct from necrosis. Although the concept of apoptosis was introduced 43 years ago (Kerr et al 1972), the mechanisms of how apoptosis is initiated and executed remained unclear until recently.