1. Beta-Lactamase Hybrid Proteins

    Beta-Lactamase Hybrid Proteins
    Introduction Beta-lactam antibiotics are used to treat a broad spectrum of Gram-positive and Gram-negative bacteria.   β-lactam antibiotics target the penicillin-binding proteins (PBPs) - a group of enzymes found attached in the cell membrane, which are involved in the cross-linking of the bacterial cell wall. The β-lactam ring portion of this group of antibiotics binds to these different PBPs, rendering them...

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