• The Ultimate Guide to Beta Lactamase 2018-11-20 11:30:59 Beta Lactamase Mechanism Beta lactam antibiotics, like cephams and penicillin derivatives, have a four-member cyclic amide ring that inhibits the peptidoglycan layer synthesis in bacteria. A woven complex of sugar and protein pieces, these first-class bactericidal drugs destroy the integrity of
  • Beta-Lactamase Hybrid Proteins 2018-11-06 12:38:35 Introduction Beta-lactam antibiotics are used to treat a broad spectrum of Gram-positive and Gram-negative bacteria.   β-lactam antibiotics target the penicillin-binding proteins (PBPs) – a group of enzymes found attached in the cell membrane, which are involved in the cross-linking Beta Lactam Antibiotics
  • Beta Lactamase Inhibitors in Research: Anti-Seizure 2016-10-24 16:00:22 Beta-lactam antibiotics contain a cyclic amide ring of which mimics the structure of the terminal amino acid residues comprising the peptidoglycan matrix. It is this structure that the enzyme beta lactamase acts upon as a method of antibiotic defense, hydrolyzing the ring and compromising the struct
  • Top 7 FAQs for Beta Lactamase enzyme 2016-08-19 16:00:38 As a core structure in many antibiotics, beta lactam ring is a cyclic amide. Beta lactam antibiotics almost universally inhibits bacterial cell wall synthesis and thus induces the destruction of the bacteria cell. Bacteria have evolved an enzyme that combats this antibiotic and increases resistance
  • Novel reporter system for monitoring gene expression 2013-07-11 09:22:13 To gain insightful information about the mechanisms through which genes are activated and repressed requires gene reporter systems that are sensitive, robust, and cost-effective. Although numerous reporter gene technologies are commercially available, none are as sophisticated and user-friendly