1. Detergents: Important Tools for Membrane Protein Purification

    Detergents: Important Tools for Membrane Protein Purification
    Membrane Proteins Proteins control almost all functions of a cell. Any mutation in protein structure or any issue hampering protein functionality can lead to abnormal cell processes, which can in turn result in disease. Therefore it is very important to meticulously learn and get a better understanding of proteins in order to find therapies for diseases plaguing humanity. Integral membrane...
  2. Protein Solubilizers aka Protein Biodetergents

    Non-ionic detergents contain uncharged, hydrophilic head groups that consist of eithermicelle polyoxyethylene moieties as in TWEEN and TRITON or glycosidic groups as in octyl glucoside and dodecyl maltoside. In general, non-ionic detergents are better suited for breaking lipid-lipid and lipid-protein interactions than protein-protein interactions.

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