1. Digitonin as a Biological Detergent

    Digitonin as a Biological Detergent
    Digitonin (C56H92O29) is a steroidal, monodesmosidic saponin (a toxic chemical with a plant-based origin) derived from the foxglove plant species, Lady’s Glove; Digitalis pupurea. The compound appears as a white or off-white powder under room temperature, and scientists often apply it as a biological detergent due to its capacity to water-solubilize lipids.  The compound naturally occurs as a non-ionic surfactant...
  2. Tips for Selecting Biological Detergents

    Tips for Selecting Biological Detergents
    Tips for Selecting Biological Detergents Biological detergents are chemicals classified as surfactants, or surface-active molecules. Research scientists typically use these detergents in affecting the interactions within molecules of a biological sample being studied. These surfactants are used in biochemical research to target and manipulate the structure of membrane proteins without sacrificing their integrity or impacting their original function. Membrane proteins...
  3. 18 Fast Facts about CHAPS Detergent

    18 Fast Facts about CHAPS Detergent
    1. What are Bio Detergents? Detergents are soluble amphiphilic molecules that are able to incorporate to liposomes and cell membranes. They are essential tools for the study of biological membranes, as they are frequently used to solubilize membrane proteins and to investigate the interactions among membrane lipid components.   2. What are the different types of biological detergents? Ionic detergents...
  4. 26 FAQS on Octyl-glucoside, (OG) biodetergent

    A non-ionic detergent intended for solubilizing membrane-bound proteins in theirnative state and for the preparation of lipid vesicles. Its well defined chemical structure, small uniform micelles and high water solubility make it superior to most other non-ionic detergent for membrane solubilization.
  5. Non-Ionic Protein Solubilizers (Non-Ionic Detergents)

    Non-ionic detergents contain uncharged, hydrophilic head groups that consist of eithermicelle polyoxyethylene moieties as in TWEEN and TRITON or glycosidic groups as in octyl glucoside and dodecyl maltoside. In general, non-ionic detergents are better suited for breaking lipid-lipid and lipid-protein interactions than protein-protein interactions.
  6. 9 Tips for Selecting a Biological Detergent

    9 Tips for Selecting a Biological Detergent
    The method of detergent removal can be an important consideration. If dialysis is to be employed, a detergent with a high CMC is clearly preferred. Alternatively, if ion exchange chromatography is utilized, a non-ionic detergent (e.g. n-Octyl-β-D-Glucopyranoside, OG, O-1036 see structure,OCTYL-GLUCOSIDE DDM, D-1304) or a sulfobetaines.

6 Item(s)

To Top