• The Ultimate Guide to Beta Lactamase 2018-11-20 11:30:59 Beta Lactamase Mechanism Beta lactam antibiotics, like cephams and penicillin derivatives, have a four-member cyclic amide ring that inhibits the peptidoglycan layer synthesis in bacteria. A woven complex of sugar and protein pieces, these first-class bactericidal drugs destroy the integrity of
  • Bafilomycin as a Cancer Treatment 2017-07-05 08:48:17 Bafilomycins are a family of toxic macrolide antibiotics isolated from Streptomyces species. AG Scientific offers several high-quality bafilomycin products. Bafilomycins at AG Scientific Product Number Product Name B-1183 Bafilomycin A1 B-1185 Bafilomycin B1 B-1245 Bafilomycin B2 B-2535 Bafilomycin Microscopy
  • CHIR 99021 GSK3 Inhibitor’s Role in Stem Cell Research 2017-02-09 11:21:43 Stem cell therapies are the leading and most sensational topic in the world of scientific research. The excitement is due to the huge potential these cells have in curing human diseases. What are stem cells? They are undifferentiated cells in human body that are capable of differentiating into speci
  • Thapsigargin Applications: Glioblastoma Multiforme Studies 2016-12-16 16:02:54 Glioblastoma multiforme is the most aggressive and malignant form of gliomas, a group of tumors arising from glial cells of the brain. Glioblastomas are very difficult to treat due to the diffused nature of the tumor itself. The tumor cells have a distinct invasive feature of spreading and diffusing
  • A Promising Cancer Therapy: Thapsigargin’s Anti-Cancer Roles 2016-12-06 16:00:21 Thapsia Garganica is a common Mediterranean weed  highly toxic to sheep and cattle, thus earning the nickname “death carrot”. Thapsigargin is a natural cytotoxin derived from the plant Thapsia Graganica. Oncologists Samuel Denmeade at Johns Hopkins Un
  • What is Thapsigargin: Thapsigargin FAQ 2016-12-02 17:51:00 Thapsigargin is a naturally occurring tumor promoter derived from the plant Thapsia garganica. This effect is a result of emptying the intracellular calcium stores, which leads to a chain of events that causes apoptosis. What is thapsigargin? Thapsigargin is a naturally occurring sesquit
  • Oncologic Neurosurgery: My Awake Brain Surgery 2016-10-21 16:00:57 Photograph: CEO Chip Lindgren and Dr. Linda M. Liau (His Neurosurgeon.) In June 2001, our CEO Chip Lindgren suddenly found out he was diagnosed with oligodendroglioma brain cancer. He was able to buy time with world leading surgeons that have over watched breakthroughs in can
  • Cachexia: Researching the Wasting Disease 2016-08-03 14:14:05 The Last Illness As if being diagnosed with advanced cancer or COPD was not bad enough news, patients with these hardcore diseases face the risk of also being afflicted with an illness that disrupts their appetite and metabolism which eventually leads to body mass loss and ca
  • National Cancer Moonshot Initiative (2016) – Announced: Blue Ribbon Panel 2016-04-18 18:00:50 Themes the Blue Ribbon Panel will discuss in the coming months: cancer vaccines highly sensitive approaches to early detection advances in immunotherapy and combination therapies single cell genomic profiling of cancer cells and cells in the tumor microenvironment enhanced data sharing new approache blue ribbon panel
  • Tweaking The Immune System Can Help Fight Cancer & Block Angiogenesis 2013-08-06 09:36:39 Cancers that become resistant to an important class of drugs might be made vulnerable by tweaking the immune system, a team led by UCSD researcher Napolene Ferrara has found.