1. How Safe Is Your Water?

    How Safe Is Your Water?
      Water Contamination The common causes of acute diarrhea are viruses and bacteria. Diarrhea is a symptom of infections caused by a host of bacterial, viral and parasitic organisms, most of which are spread by feces-contaminated water. Escherichia coli (E. coli) are a large and diverse group of bacteria. Although most strains of E. coli are harmless, others can make...
  2. CK-666: Inhibitor of Actin-Related Proteins

    CK-666: Inhibitor of Actin-Related Proteins
    Actin is a family of globular multi-functional proteins that form microfilaments. Microfilaments, also called actin filaments, are filaments in the cytoplasm of eukaryotic cells that form part of the cytoskeleton. Actin participates in many important cellular processes, including muscle contraction, cell motility, cell division and cytokinesis, vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions...
  3. Bafilomycin as a Cancer Treatment

    Bafilomycin as a Cancer Treatment
    Bafilomycins are a family of toxic macrolide antibiotics isolated from Streptomyces species. AG Scientific offers several high-quality bafilomycin products. Bafilomycins at AG Scientific Product Number Product Name B-1183 Bafilomycin A1 B-1185 Bafilomycin B1 B-1245 Bafilomycin B2 B-2535 Bafilomycin C1 B-2537 Bafilomycin D Bafilomycins in Cancer Research The most commonly used bafilomycin is bafilomycin A1 (Baf-A1). Baf-A1 is an autophagy inhibitor...
  4. Detergents: Important Tools for Membrane Protein Purification

    Detergents: Important Tools for Membrane Protein Purification
    Membrane Proteins Proteins control almost all functions of a cell. Any mutation in protein structure or any issue hampering protein functionality can lead to abnormal cell processes, which can in turn result in disease. Therefore it is very important to meticulously learn and get a better understanding of proteins in order to find therapies for diseases plaguing humanity. Integral membrane...
  5. 18 Fast Facts about CHAPS Detergent

    18 Fast Facts about CHAPS Detergent
    1. What are Bio Detergents? Detergents are soluble amphiphilic molecules that are able to incorporate to liposomes and cell membranes. They are essential tools for the study of biological membranes, as they are frequently used to solubilize membrane proteins and to investigate the interactions among membrane lipid components.   2. What are the different types of biological detergents? Ionic detergents...
  6. 12 facts about Lactate Oxidase

    12 facts about Lactate Oxidase
    Lactate detection and quantification plays a vital role in healthcare, especially in conditions such as hemorrhage, sepsis, tissue hypoxia, respiratory failure and kidney failure. It also has a key role in sports medicine where it is essential in monitoring athletes. Lactate Oxidase is an enzyme which is predominantly used in the detection of Lactate. This has led to development of...
  7. CHIR 99021 GSK3 Inhibitor’s Role in Stem Cell Research

    CHIR 99021 GSK3 Inhibitor’s Role in Stem Cell Research
    Stem cell therapies are the leading and most sensational topic in the world of scientific research. The excitement is due to the huge potential these cells have in curing human diseases. What are stem cells? They are undifferentiated cells in human body that are capable of differentiating into specialized cell types. Stem cells differentiate into different cell types during early...
  8. Top 10 FAQs About Inhibitor CHIR99021

    Top 10 FAQs About Inhibitor CHIR99021
    Any questions about Inhibitor CHIR99021? See all about it in the post below. What is inhibitor CHIR99021? CHIR99021 (CT99021), is also known as 6-amino]ethyl]amino]-3-pyridinecarbonitrile and CT99021. It is the most potent and selective inhibitor of GSK3. CHIR99021 is an aminopyrimidine derivative. It inhibits GSK3 β and GSK3 α. It also functions as a WNT activator. It is the most selective...
  9. Cancer Treatment Combination of Paclitaxel, Rapamycin and 17-AAG

    The Wisconsin Alumni Research Foundation (WARF) is seeking commercial partners interested in developing a composition of the synergistic anticancer agents rapamycin, paclitaxel and 17-AAG, encapsulated and solubilized by nontoxic, nanoscale PEG-b-PLA micelles.
  10. Cycloheximide-induced T-cell Death Is Mediated by a Fas-associated Death Domain-dependent Mechanism

    Cycloheximide (CHX) can contribute to apoptotic processes, either in conjunction with another agent (e.g. tumor necrosis factor-α) or on its own. The apoptotic process is now known to involve the well orchestrated interactions of cell death receptors, death receptor adaptors, caspases, and Bcl-2 family members.

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