The CHIR99021 GSK-3 Inhibitor is both potent and selective. Small membrane-permeable molecules are widely utilized for maintenance and differentiation of embryonic stem cells (ES) of different species. Glycogen synthase kinase 3 (GSK3) activates the Wnt/beta-catenin pathway when targeted for inhibition. GSK3 is a conserved signaling molecule with essential roles in diverse biological processes. GSK3 activity has been linked to a...
In todayâ€™s modern world, the recent dramatic increase in the number of patients with type 2 diabetes indicates an unchecked global epidemic is at hand. In 2011 the U.S. Centers for Disease Control and Prevention estimated that about 8.3% of the American population (25.8 million people) had diabetesâ€”while 7 million were unaware of it.