1. Breaking News (2016) - HIV Drug May Treat Alzheimer's Disease

    Breaking News (2016) - HIV Drug May Treat Alzheimer's Disease
    Scientists at Case Western University, under the support in part by the Public Health Service Grant, was able to map the allosteric site in Cholesterol Hydroxylase CYP46A1 for efavirenz, a drug used to treat HIV infections, that stimulates enzyme activity. What they Found CYP46A1 is an enzyme responsible for 80 percent of the cholesterol breakdown in the human brain. Efavirenz...
  2. Protease Inhibitors: Killing Viral Replication

    Protease Inhibitors: Killing Viral Replication
    What Is a Protease Inhibitor? To best explain what a protease inhibitor is, let's start with a basic review of the biology of viruses, such as HIV. Firstly, HIV is a virus that attacks the immune system by infecting cells of the immune system. The infection does not kill the cell immediately, but HIV forces the infected cell to make...

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