1. A23187: Uncouples Oxidative Phosphorylation and Inhibits ATPase

    A23187: Uncouples Oxidative Phosphorylation and Inhibits ATPase Chemical structure of calcium ionophore A23187 A23187 is a carboxylic acid antibiotic which simultaneously uncouples oxidative phosphorylation and inhibits ATPase of rat liver mitochondria incubated in a magnesium-free medium. The antibiotic acts as a freely mobile carrier to transport calcium and magnesium, but not potassium, from an aqueous medium buffered at pH 7.4...

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