1. Rapamycin: Most Commonly Asked Questions

    Rapamycin: Most Commonly Asked Questions
    Discovery of Rapamycin Rapamycin is a macrocyclic triene antibiotic that binds to the cytosolic protein FK-binding protein 12 (FKBP12) and inhibits mTOR pathway by directly binding to the mTOR Complex 1 (mTORC1). It is a potent immunosuppressant having a variety of uses both in vitro and in vivo and is used to prevent organ rejection after transplantation. Chemical structure of...
  2. MYCOPHENOLIC ACID PREVENTS REJECTION IN ORGAN TRANSPLANTATION

    Mycophenolic acid or mycophenolate is an immunosuppressant drug used to prevent rejection in organ transplantation. It inhibits an enzyme needed for the growth of T cells and B cells. It was initially marketed as the prodrugmycophenolate mofetil (MMF) to improve oral bioavailability. More recently, the salt mycophenolate sodium has also been introduced. Mycophenolic acid is commonly marketed under the trade...
  3. 29 RAPAMYCIN IMMUNOSUPPRESSANT FACTS

    Rapamycin, also known as sirolimus, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.
  4. What is the Immunosuppressant Treatment?

    An immunosuppressant is any substance that performs immunosuppression of the immunedescribe the image system. They may be either exogenous, as immunosuppressive drugs, or endogenous, as, e. g., testosterone. When the immune system function is suppressed, there is an increased susceptibility to infectious diseases and cancers.

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