Bacteriocidal antibiotics obtained from Streptomyces that inhibit protein synthesis in bacterial ribosomes and are effective against aerobic gram-negative bacilli. This group of antibiotics includes at least eight drugs: amikacin,gentamicin, kanamycin, neomycin, netilmicin, paromomycin, streptomycin, and tobramycin. All of these drugs have the same basic chemical structure.
Puromycin is an aminonucleosidic antibiotic. Puromycin is a protein synthesis inhibitor by inhibiting translation. Puromycinâ€™s main function is used in cell biology as a selective antibiotic agent in cell culture systems.