1. Calyculin A: Potent Tumor Promoter Used in Mouse Skin Experiment

    Calyculin A, a marine toxin isolated from Disodermia calyx, is a structurally distinct inhibitor of PP1 (protein phosphatase 1) and protein phosphatase 2A (PP2). It has been shown that Calyculin A displays inhibitory properties towards the endogenous phosphatase of smooth muscle myosin B and induces contraction in the muscle fibers.

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