1. Bestatin (Ubenimex): Applications in Life Science Research

    Bestatin (Ubenimex): Applications in Life Science Research
    Bestatin, also known as Ubenimex, is a competitive protease inhibitor. It is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. It is being studied for use in the treatment of acute myelocytic leukemia.
  2. Protease Inhibitors: Killing Viral Replication

    Protease Inhibitors: Killing Viral Replication
    What Is a Protease Inhibitor? This is best explained with a basic understanding of HIV biology. Firstly, HIV is a virus that attacks the immune system by infecting cells of the immune system. The infection does not kill the cell immediately, but HIV forces the infected cell to make more copies of itself. Copies leave the infected cell and travel...
  3. AEBSF AS A KEY BIOMARKER

    AEBSF or 4-(2-Aminoethyl) benzenesulfonyl fluoride hydrochloride is a water-soluble, irreversible serine protease inhibitor with a molecular weight of 239.5 Da. It inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. The specificity is similar to the inhibitor PMSF, nevertheless, AEBSF is more stable at low pH values. Typical usage is 0.1 - 1.0 mM. AEBSF is used as a protease...
  4. E-64, Cysteine Protease Inhibitor: Frequently Asked Questions

    E-64, Cysteine Protease Inhibitor: Frequently Asked Questions
    Irreversible, potent and highly selective inhibitor of cysteine proteases. Does not affect cysteine residues in other enzymes. Acts by forming a thioether bond with thiol of the active cysteine. E-64 will not inhibit serine proteases (except trypsin) inhibits activation-induced programmed cell death and restores defective immune responses in HIV+ donors. Specific active site titrant.

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