1. FAQs About Aprotinin Serine Protease Inhibitor

    FAQs About Aprotinin Serine Protease Inhibitor
    Initially named "kallikrein inactivator, Aprotinin was first isolated from cow parotid glands in 1930. As a pancreatic enzyme inhibitor, it was initially used in the treatment for acute pancreatitis, a condition in which the destruction of the gland by its own enzymes is thought to be part of the pathogenesis. Bovine pancreatic trypsin inhibitor (BPTI) is one of the most thoroughly...
  2. Protease Inhibitors: Killing Viral Replication

    Protease Inhibitors: Killing Viral Replication
    What Is a Protease Inhibitor? To best explain what a protease inhibitor is, let's start with a basic review of the biology of viruses, such as HIV. Firstly, HIV is a virus that attacks the immune system by infecting cells of the immune system. The infection does not kill the cell immediately, but HIV forces the infected cell to make...
  3. Exploring the uses of pepstatin A

    Pepstatin A is of microbial origin and is an N-acyl-pentapeptide, more accurately: isovaleryl-L-valyl-L-valyl-statyl-L-alanyl-statine. Pepstatin A was found to be a potent competitive inhibitor of most aspartic proteases but a weak inhibitor of renin.
  4. What are Biomarkers?

    Biomarkers are substances, structures, or processes that can be measured in biological samples such as urine, blood, or saliva. A biomarker is a measurable characteristic in a biological system that changes due to disease, exposure to chemicals, or exposure to organisms.

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