• Protease Enzymes – Common Applications 2018-11-06 01:00:19 Introduction to Protease Enzymes There are five families of proteases in which serine (eg: proteinase K/protease K/endopeptidase K), threonine, cysteine, aspartic or metallic groups play a primary catalytic role. Protease enzymes break the long chain-like molecules of proteins into shorter fragments
  • Part 2: Solving Mysteries with Trypsin and Proteinase K 2018-11-05 17:17:39 In Part 1, we discussed using trypsin on bone specimens as a cleaning alternative to sanding in preparation for DNA extraction. In this second part of the series, we cover the details of attaining a higher yield of DNA using proteinase K. Proteinase K for Higher DNA Yield from Bone Specimens DN Proteinase K
  • Part 1: Solving Mysteries with Trypsin and Proteinase K 2018-11-04 23:10:39 Identifying Human Remains Human remains are fascinating. They have many properties that can be used to identify a person: distinct scars, special features, dental x-rays, fingerprint comparisons, or physical facial characteristics. Forensic scientists attempt to identify human skeletal remains in si
  • Attaining High DNA Yield from Sperm Cells using Proteinase K 2018-02-27 12:42:07 There are many techniques that can be used to isolate high quality and high molecular weight DNA from mammalian somatic cells. However, these techniques are ineffective for mammalian sperm. Unlike somatic cells, nearly all histones in sperm cells are replaced by protamines held together by disulfide proteinase k
  • Cathepsins – FAQs 2016-05-19 00:13:46 What are Cathepsins? Cathepsins are proteases, which degrade proteins, found in all animals and other organisms. There are about a dozen members of this family distinguished by their structure, catalytic mechanism, and which proteins they cleave. When do most members become activated? They are activ Cathepsin
  • Protease Inhibitors: Killing Viral Replication 2015-12-12 00:51:39 What Is a Protease Inhibitor? This is best explained with a basic understanding of HIV biology. Firstly, HIV is a virus that attacks the immune system by infecting cells of the immune system. The infection does not kill the cell immediately, but HIV forces the infected cell to make more copies of it protease inhibitors
  • Top 4 Scientific Articles on Protease Activity 2015-11-23 14:26:20 Listed below are some articles that are of great reference for those interested in examining protease activity and their relationships to carbon and nitrogen, as well as their characterization. Click on the titles to follow the article. 1. Proteolytic activity in soil: A revi
  • Why should it be A.G. Scientific’s HRV3C Protease? 2012-06-08 11:37:12 Human rhinovirus 3C protease (HRV 3C Protease) is a cysteine protease that recognizes the cleavage site of Leu-Glu-Val-Leu-Phe-Gln-Gly-Pro, commonly referred to as the PreScission Site. It cleaves between Gln and Gly. The recombinant form of the HRV3C protease is a restriction grade protease that ha