1. 20 FACTS ABOUT PROTEASOMES & PROTEASOME INHIBITORS!

    1. Proteasome inhibitors are drugs that block the action of proteasomes, cellular complexes that break down proteins, like the p53 protein. Proteasome inhibitors are being studied in the treatment of cancer, especially multiple myeloma.
  2. Proteasome Inhibitor MG132 Induces Death Receptor

    Combined treatment with a proteasome inhibitor and tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) is a promising strategy for cancer therapy.

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