1. Digitonin as a Biological Detergent

    Digitonin as a Biological Detergent
    Digitonin (C56H92O29) is a steroidal, monodesmosidic saponin (a toxic chemical with a plant-based origin) derived from the foxglove plant species, Lady’s Glove; Digitalis pupurea. The compound appears as a white or off-white powder under room temperature, and scientists often apply it as a biological detergent due to its capacity to water-solubilize lipids.  The compound naturally occurs as a non-ionic surfactant...
  2. n-Dodecyl-β-D-maltopyranoside

    n-Dodecyl-β-D-maltopyranoside
    Any scientist involved in proteomics or protein engineering, will stand by the fact that detergents are indispensable tools for isolation and solubilization of integral membrane proteins and protein complexes from biological membranes. For these studies, it is very important to have intact protein structures in their native biological form in order to evaluate their structure, function, dynamics and binding of...
  3. Sulfobetaines, Zwitterionic Biodetergents in Diagnostics

    Improving reagent performance in immunoassays both to enhance assay sensitivity and to minimize interference are ongoing challenges in clinical diagnostics. We describe herein the syntheses of a new class of hydrophilic reagents containing sulfobetaines zwitterions and their applications.

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