1. Thapsigargin Applications: Glioblastoma Multiforme Studies

    Thapsigargin Applications: Glioblastoma Multiforme Studies
    Glioblastoma multiforme is the most aggressive and malignant form of gliomas, a group of tumors arising from glial cells of the brain. Glioblastomas are very difficult to treat due to the diffused nature of the tumor itself. The tumor cells have a distinct invasive feature of spreading and diffusing into different parts of the brain. This characteristic feature of these...
  2. Oncologic Neurosurgery: My Awake Brain Surgery

    Oncologic Neurosurgery: My Awake Brain Surgery
    Photograph: CEO Chip Lindgren and Dr. Linda M. Liau (His Neurosurgeon.) In June 2001, our CEO Chip Lindgren suddenly found out he was diagnosed with oligodendroglioma brain cancer. He was able to buy time with world leading surgeons that have over watched breakthroughs in cancer immunotherapy (immuno-oncology) and viral oncology research. Chip was one of the first to receive awake...
  3. The Role of E-64D in Amyloid Plaque Prevention

    The Role of E-64D in Amyloid Plaque Prevention
    Alzheimer's  disease is characterized by accumulation of a variety of amyloid beta (Aβ) peptides as oligomers (twisted tangles of protein) and amyloid plaques (abnormal clusters of protein fragments) in the brain. These are factors involved in neuronal loss and memory deficits over time. The neurotoxic Aβ peptides are created when enzymes cleave a large protein called amyloid precursor protein (APP...
  4. UCSD-Led Team Finds Leukemia-Killing Molecule

    UC San Diego researchers say they've found an immune system molecule that directly kills chronic lymphocytic leukemia cells without harming healthy ones. The molecule, called a monoclonal antibody, is being readied for human clinical trials in the not-too-distant future, lead researcher Thomas J. Kipps said. Kipps holds the Evelyn and Edwin Tasch Chair in Cancer Research at the UCSD Moores...

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