BMS-599626

SKU
B-2207
  • CAS:873837-23-1
  • Formula:C27H27FN8O3.HCl
  • MW:567.01
  • Appearance:Crystalline Solid
  • Purity:99%
Product Name Qty
BMS-599626
1 mg
$336.03
BMS-599626
5 mg
$1,019.47
An orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.
More Information
Alternate Name/Synonyms
AC480
SKU
B-2207
CAS #
873837-23-1
Chemical Name
(S)-MORPHOLIN-3-YLMETHYL 4-(1-(3-FLUOROBENZYL)-1H-INDAZOL-5-YLAMINO)-5-METHYLPYRROLO[1,2-F][1,2,4] TRIAZIN-6-YLCARBAMATE
Chemical Formula
C27H27FN8O3.HCl
Molecular Weight
567.01
Appearance
Crystalline Solid
Purity
99%
Solubility
DMSO
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
An orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity
MDL NUMBER
MFCD10565678
CHEMACX
X1812385-6
INCHI
InChI=1S/C27H27FN8O3/c1-17-23(34-27(37)39-15-22-14-38-8-7-29-22)13-36-25(17)26(30-16-32-36)33-21-5-6-24-19(10-21)11-31-35(24)12-18-3-2-4-20(28)9-18/h2-6,9-11,13,16,22,29H,7-8,12,14-15H2,1H3,(H,34,37)(H,30,32,33)/t22-/m0/s1
SMILES
CC1=C2C(=NC=NN2C=C1NC(=O)OC[C@@H]3COCCN3)NC4=CC5=C(C=C4)N(N=C5)CC6=CC(=CC=C6)F
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and moisture
GHS PICTOGRAMS
HandlingProtect from air and moisture
UN #'SNot Applicable
Packing GroupNot Applicable
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