- MW:537.7 Da
- Appearance:Lyophilized solid
Bongkrekic acid is an inhibitory ligand of the mitochondrial adenine nucleotide translocase (ANT) the inner membrane channel of the mitochondrial permeability transition pore (MPTP). It is a natural toxin when it contaminates food products.
It is a polyunsaturated long-chain fatty acid derivative that acts as a potent inhibitor of ANT. This acid blocks NMDA receptor and prevents PARP cleavage and DEVDase(Caspase-2 like) activity so that it inhibits apoptosis of cerebrocortical neurons.
Not for human therapeutic use or for medicinal purposes. For research applications only.
|Handling||Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product.|