BQ-788 Sodium Salt

SKU
E-1034
  • CAS:156161-89-6
  • Formula:C34H50N5O7Na
  • MW:663.7
  • Appearance:White to off-white Powder
  • Purity:95%

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Product Name Qty
BQ-788.Sodium Salt
500 ug
$167.51
BQ-788 Sodium Salt
1 mg
$279.18
A highly potent and selective ETB-receptor antagonist.
More Information
Alternate Name/Synonyms
ETB-Receptor Antagonist [N-cis-2,6-Dimethylpiperidinocarbonyl-L-yMeLeu-D-Trp(COOMe)-D-Nle-Ona
SKU
E-1034
CAS #
156161-89-6
Chemical Name
N-cis-2,6-Dimethylpiperidinocarbonyl-L-yMeLeu-D-Trp(COOMe)-D-Nle-Ona
Chemical Formula
C34H50N5O7Na
Molecular Weight
663.7
Appearance
White to off-white Powder
Purity
95%
Solubility
Soluble in DMSO (25mg/ml), slightly soluble inethanol
Storage Temp
-20°C
THERAPEUTIC AREA
Cardiological Disorders
USE
BQ 788 sodium salt is a selective ETBR (Endothelin receptor B ) antagonist used for chronic heart failure
MDL NUMBER
MFCD00797882
CHEMACX
X1087537-5
INCHI
InChI=1S/C34H51N5O7.Na/c1-8-9-16-25(31(42)43)35-29(40)26(18-23-20-38(33(45)46-7)28-17-11-10-15-24(23)28)36-30(41)27(19-34(4,5)6)37-32(44)39-21(2)13-12-14-22(39)3;/h10-11,15,17,20-22,25-27H,8-9,12-14,16,18-19H2,1-7H3,(H,35,40)(H,36,41)(H,37,44)(H,42,43);/q;+1/p-1/t21-,22+,25-,26-,27+;/m1./s1
SMILES
CCCC[C@H](C(=O)[O-])NC(=O)[C@@H](CC1=CN(C2=CC=CC=C21)C(=O)OC)NC(=O)[C@H](CC(C)(C)C)NC(=O)N3[C@@H](CCC[C@@H]3C)C.[Na+]
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Store in Tightly Sealed Vial
Citations
HEMODYNAMICS AND VASCULAR REGULATION: Lack of Endothelial Nitric Oxide Synthase Promotes Endothelin-Induced Hypertension: Lessons from Endothelin-1 Transgenic/Endothelial Nitric Oxide Synthase Knockout Mice Thomas Quaschning, Florian Voss, Katharina Relle, Philipp Kalk, Nicolas Vignon-Zellweger, Thiemo Pfab, Christian Bauer, Franziska Theilig, Sebastian Bachmann, Annette Kraemer-Guth, Christoph Wanner, Franz Theuring, Jan Galle, and Berthold Hocher J. Am. Soc. Nephrol., Mar 2007; 18: 730 - 740.
Citations_Hyperlink
http://jasn.asnjournals.org/cgi/reprint/18/3/730
Certificate of Analysis 1
Certificate of Analysis 2
Handling Store in Tightly Sealed Vial
UN #'S Not Applicable
Packing Group Not Applicable
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