Butyrolactone I

SKU
B-2211
  • CAS:87414-49-1
  • Formula:C24H24O7
  • MW:424.44
  • Appearance:White Solid
  • Purity:99% by HPLC

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Product Name Qty
Butyrolactone I
200 ug
$128.43
Cell permeable. A potent and selective inhibitor of the cyclin-dependent kinases CDK1/cyclin B, CDK2 and CDK5. Inhibits cell cycle progression at the G1/S and G2/M transitions. BLI is an important tool for probing the cellular roles of CDKs. It blocks Fas-induced apoptosis and displays antitumor activity.
More Information
Alternate Name/Synonyms
BLI, BL-I
SKU
B-2211
CAS #
87414-49-1
Chemical Name
METHYL-4-HYDROXY-2-[[4-HYDROXY-3-(3-METHYLBUT-2-ENYL)PHENYL]METHYL]-3-(4-HYDROXYPHENYL)-5-OXOFURAN-2-CARBOXYLATE
Chemical Formula
C24H24O7
Molecular Weight
424.44
Appearance
White Solid
Purity
99% by HPLC
Solubility
Soluble in DMSO (10 mg/ml) and Ethanol (25 mg/ml)
Stability
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Antitumor effects of butyrolactone I, a selective cdc2 kinase inhibitor, on human lung cancer cell
MDL NUMBER
MFCD03453074
CHEMACX
X1192611-1
INCHI
InChI=1S/C24H24O7/c1-14(2)4-6-17-12-15(5-11-19(17)26)13-24(23(29)30-3)20(21(27)22(28)31-24)16-7-9-18(25)10-8-16/h4-5,7-12,25-27H,6,13H2,1-3H3
SMILES
CC(=CCc1cc(ccc1O)CC2(C(=C(C(=O)O2)O)c3ccc(cc3)O)C(=O)OC)C
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
Promo text for AGS discount
N/A
GHS PICTOGRAMS
Handling Protect from air and light
UN #'S Not Applicable
Packing Group Not Applicable
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