Calpain Inhibitor III
- Appearance:White lyophilized Solid
- Purity:≥95% by HPLC
A potent, cell-permeable inhibitor of calpain I and II (K = 8 nM).That also reduces capsaicin-mediated cell death in cultured dorsal root ganglion. Reported to block A23187-induced suppression of neurite outgrowth in isolated hippocampal pyramidal neurons. Exhibits neuroprotective effect in glutamate-induced toxicity.
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