Calpain Inhibitor III

SKU
C-1549
  • CAS:88191-84-8
  • Formula:C22H26N2O4
  • MW:382.5
  • Appearance:White lyophilized Solid
  • Purity:≥95% by HPLC

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Product Name Qty
Calpain Inhibitor III
10 mg
$61.42
Calpain Inhibitor III
50 mg
$240.10
Calpain Inhibitor III  (MDL 28170)
25 mg
$156.34

A potent, cell-permeable inhibitor of calpain I and II (K = 8 nM).That also reduces capsaicin-mediated cell death in cultured dorsal root ganglion. Reported to block A23187-induced suppression of neurite outgrowth in isolated hippocampal pyramidal neurons. Exhibits neuroprotective effect in glutamate-induced toxicity.

More Information
Alternate Name/Synonyms
MDL 28170,  Z-Val-Phe-CHO
SKU
C-1549
CAS #
88191-84-8
Chemical Name
BENZYL-N-[(2S)-1-OXO-3-PHENYLPROPAN-2-YL]CARBAMATE
Chemical Formula
C22H26N2O4
Molecular Weight
382.5
Appearance
White lyophilized Solid
Purity
≥95% by HPLC
Solubility
10 mg/ml in DMSO or ethanol, insoluble in water
Storage Temp
-20°C
THERAPEUTIC AREA
Neurological Disorders
USE
A cell permeable selective inhibitor of Calpain 1, has neuroprotective effects in spinal cord injury.
MDL NUMBER
MFCD00798796
CHEMACX
X1271586-5
INCHI
InChI=1S/C22H26N2O4/c1-16(2)20(24-22(27)28-15-18-11-7-4-8-12-18)21(26)23-19(14-25)13-17-9-5-3-6-10-17/h3-12,14,16,19-20H,13,15H2,1-2H3,(H,23,26)(H,24,27)/t19-,20-/m0/s1
SMILES
CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C=O)NC(=O)OCC2=CC=CC=C2
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Certificate of Analysis 1
Certificate of Analysis 2
Promo text for AGS discount
N/A
UN #'S Not Applicable
Packing Group Not Applicable
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