SDS
CofA
Description
Calyculin A is a marine toxin which inhibits protein phosphatase 2A and protein phosphatase 1. Calyculin A is also a potent non-phorbol tumor promoter. Calyculin A prevents γ-radiation induced apoptosis.
Not for human therapeutic use or for medicinal purposes. For research applications only.
More Information
Alternate Name/Synonyms
(-)-calyculin A; Calyculin
SKU
C-1031
CAS #
101932-71-2
Chemical Name
N-[(3S)-3-[4-[(1E)-3-[(2R,3R,5R,7S,8S,9R)-2-[(1S,3S,4S,5R,6R,7E,9E,11E,13Z)-14-cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyl-7,9,11,13-tetradecatetraen-1-yl]-9-hydroxy-4,4,8-trimethyl-3-(phosphonooxy)-1,6-dioxaspiro[4.5]dec-7-yl]-1-propen-1-yl]-2-o
Chemical Formula
C50H81N4O15P
Molecular Weight
1009.2
Appearance
Solid
Purity
≥99%
Solubility
Soluble in organic solvents such as ethanol and DMSO, which should be purged with an inert gas.
Storage Temp
-20ºC
USE
Protein phosphatase 1 and protein phosphatase 2A inhibitor. Potent non-phorbol tumor promoter.
Handling
Avoid breathing dust/fume/gas/mist/vapours/spray. Avoid prolonged or repeated exposure.
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
| GHS PICTOGRAMS |   |
|---|---|
| Handling | Avoid breathing dust/fume/gas/mist/vapours/spray. Avoid prolonged or repeated exposure. |
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