- Formula:C20H22N4O5 • CH3SO3H
- MW:494.5 Da
- Appearance:Off-white powder
- Purity:>98% by HPLC
A serine protease inhibitor inhibiting plasmin, kallikrein, thrombin as well as trypsin, which attenuates pancreatic fibrosis1 . Reduces weight gain and improves metabolism in obese rodent models2 . In clinical use (in Japan) for pancreatitis3 . Inhibits influenza virus replication in human tracheal epithelial cells4 . Reduces infection of Calu-3 lung cells by SARS-CoV-2 (responsible for COVID-19) via inhibition of the serine protease TMPRSS2 required for viral spike protein priming5 .
Shown to be effective against coronavirus.
Not for human therapeutic use or for medicinal purposes. For research applications only.
|Handling||Use personal protective equipment as required. Avoid contact with skin, eyes or clothing. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Use with local exhaust ventilation|