Cantharidin

SKU
C-1412
  • CAS:56-25-7
  • Formula:C10H12O4
  • MW:196.2 Da
  • Appearance:White powder
  • Purity:>98% by HPLC

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Product Name Qty
Cantharidin, Specific protein phosphatase 2A inhibitor
25 mg
$134.01
Cantharidin, Specific protein phosphatase 2A inhibitor
10 mg
$70.36

Acts as a potent and selective inhibitor of protein phosphatase 2A. Also inhibits protein phosphatase 1 at higher concentrations. Useful in inhibition of PP and PP during purification of phosphorylated porteins.

More Information
Alternate Name/Synonyms
Cantharidine; Cantharone; Kantaridin; Kantharidin; Cantharides camphor
SKU
C-1412
CAS #
56-25-7
Chemical Name
(1R,2S,6R,7S)-2,6-dimethyl-4,10-dioxatricyclo[5.2.1.02,6]decane-3,5-dione
Chemical Formula
C10H12O4
Molecular Weight
196.2 Da
Appearance
White powder
Purity
>98% by HPLC
Solubility
Soluble in DMSO (20 mg/ml) or Ethanol (5 mg/ml)
Melting Point
215-217 °C
Preparation
N/A
Storage Temp
-20°C, desiccated
THERAPEUTIC AREA
Not Applicable
USE
Cantharidin appears to have some effect in the topical treatment of cutaneous leishmaniasis in animal models. In addition to topical medical applications, cantharidin and its analogues may have activity against cancer cells. Laboratory studies with cultured tumor cells suggest that this activity may be the result of PP2A inhibition.
Merck Index
N/A
MDL NUMBER
MFCD00134968
CHEMACX
X1000733-5
INCHI
InChI=1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10-
SMILES
C[C@@]12[C@H]3CC[C@@H]([C@@]1(C(=O)OC2=O)C)O3
RTECS
RN8575000
UN #'S
UN 2811
PACKING GROUP
I
Handling
Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Use with local exhaust ventilation. Noxious vapor/odor. Ensure adequate ventilation, especially in confined areas.
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
GHS PICTOGRAMS
Handling Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Use with local exhaust ventilation. Noxious vapor/odor. Ensure adequate ventilation, especially in confined areas.
UN #'S UN 2811
Packing Group I
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