Capecitabine

SKU
C-2217
  • CAS:154361-50-9
  • Formula:C15H22FN3O6
  • MW:359.35
  • Appearance:White to off-white solid
  • Purity:≥99% by HPLC
Product Name Qty
Capecitabine
100 mg
$74.04
Capecitabine
1 g
$518.28
A pre-prodrug of 5-fluorouracil (5-FU).  After oral uptake, capecitabine is first metabolized to 5'-deoxy-5-fluorocytidine (5'-DFCR), which occurs mainly in the liver by carboxyl-esterase.  The metabolite is converted to 5'-deoxy-5-fluoro-uridine (5'-DFUR) by cytidine deaminase in liver and tumor tissue.  Then 5'-DFUR is converted to 5-FU intracellularly by thymidine phosphorylase, which is often expressed in tumor tissue.
More Information
SKU
C-2217
CAS #
154361-50-9
Chemical Name
Pentyl[1-(3,4-dihydroxy-5-methyl-tetrahydrofuran-2-yl)- 5-fluoro-2-oxo-1H-pyrimidin- 4-yl]aminomethanoate; captabin; Ro 09-1978; Xabine
Chemical Formula
C15H22FN3O6
Molecular Weight
359.35
Appearance
White to off-white solid
Purity
≥99% by HPLC
Solubility
DMSO (100 mg/ml) or EtOH (10 mg/ml)
Storage Temp
-20°C
GHS PICTOGRAMS
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