Capreomycin

SKU
C-2605
  • CAS:11003-38-6
  • Formula:C25H44N14O7S (for IB)
  • MW:652.7 Da
  • Appearance:White solid
  • Purity:>99% by HPLC

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Product Name Qty
Capreomycin
5 mg
$145.17
Capreomycin
25 mg
$507.00

Description

Capreomycin is a complex of cyclic pentopeptides isolated from Streptomyces capreolus, first reported in 1962. The complex has two major components, IA and IB, with an exocyclic lysine residue and two minor delysinyl components, IIA and IIB. Capreomycin is a potent antibiotic with activity against mycobateria, Gram positive and Gram negative organisms. Capreomycin acts by binding to the 23S ribosomal subunit, disrupting protein synthesis

 

More Information
Alternate Name/Synonyms
Capromycin, Caprolin, Capastat, Capostatin, L 29275
SKU
C-2605
CAS #
11003-38-6
Chemical Name
(3S)-3,6-diamino-N-[[(2S,5S,8E,11S,15S)-15-amino-11-[(4R)-2-amino-1,4,5,6-tetrahydropyrimidin-4-yl]-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-8-(ureidomethylene)-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]hexanamide; (3S)-3,6-diamino-N-[[(2S,5S,8E,11S,15S)-
Chemical Formula
C25H44N14O7S (for IB)
Molecular Weight
652.7 Da
Appearance
White solid
Purity
>99% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
This medication is used with other drugs to treat tuberculosis (TB) infections
MDL NUMBER
MFCD01770630
INCHI
InChI=1S/C25H44N14O8.H2O4S/c26-4-1-2-11(27)6-17(41)32-8-14-20(43)35-15(9-34-25(30)47)21(44)39-18(13-3-5-31-24(29)38-13)23(46)33-7-12(28)19(42)37-16(10-40)22(45)36-14;1-5(2,3)4/h9,11-14,16,18,40H,1-8,10,26-28H2,(H,32,41)(H,33,46)(H,35,43)(H,36,45)(H,37,42)(H,39,44)(H3,29,31,38)(H3,30,34,47);(H2,1,2,3,4)/b15-9-;
SMILES
C1CN=C(NC1C2C(=O)NCC(C(=O)NC(C(=O)NC(C(=O)N/C(=C\NC(=O)N)/C(=O)N2)CNC(=O)CC(CCCN)N)CO)N)N.OS(=O)(=O)O
GHS PICTOGRAMS
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