Carbozantinib, CabometyxTM

SKU
C-2219
  • CAS:849217-68-1
  • Formula:C28H24FN3O5
  • MW:501.51
  • Appearance:Off-White Solid
  • Purity:98% by HPLC
Product Name Qty
Carbozantinib
5 mg
$142.38
Carbozantinib
25 mg
$552.45
Cell-permeable. A potent inhibitor of MET, vascular endothelial growth factor receptor 2 (VEGFR2), and RET, with robust antiangiogenic, antitumor, and anti-invasive effects.
More Information
Alternate Name/Synonyms
N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, Cabometyx TM
SKU
C-2219
CAS #
849217-68-1
Chemical Name
N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Chemical Formula
C28H24FN3O5
Molecular Weight
501.51
Appearance
Off-White Solid
Purity
98% by HPLC
Solubility
Soluble in DMSO
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
A potent VEGFR2 and Met inhibitor use in cancer
MDL NUMBER
Not Available
CHEMACX
X3528576-0
INCHI
InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34)
SMILES
COc1cc2c(ccnc2cc1OC)Oc3ccc(cc3)NC(=O)C4(CC4)C(=O)Nc5ccc(cc5)F
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
Certificate of Analysis 1
GHS PICTOGRAMS
HandlingProtect from air and light
UN #'SNot Applicable
Packing GroupNot Applicable
To Top