Caspase-1 Substrate YVAD-pNA

SKU
C-2228
  • Formula:C29H36N5O10
  • MW:628.6
  • Appearance:Liquid
  • Purity:98% by HPLC
Product Name Qty
Caspase-1 Substrate YVAD-pNA
1000 assays
$620.78
Caspase-1 Substrate YVAD-pNA
200 assays
$290.47

Ready-to-use colorimetric substrate for caspase-1/ICE and related caspases that recognize the amino acid sequence YVAD. Caspase-1 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l= 400 nm) after cleavage from the peptide substrate YVAD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economic alternative for large volume users.

More Information
Alternate Name/Synonyms
Ac-YVAD-pNA, Caspase-1 Substrate, Colorimetric
SKU
C-2228
Chemical Name
Ac-YVAD-pNA, Caspase-1 Substrate, Colorimetric
Chemical Formula
C29H36N5O10
Molecular Weight
628.6
Appearance
Liquid
Purity
98% by HPLC
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
A substrate for caspase-1 and caspase-4; cleavage is monitored colorimetrically at 405nm
MDL NUMBER
MFCD00274387
CHEMACX
X1086209-2
INCHI
InChI=1S/C29H36N6O10/c1-15(2)25(34-28(42)22(31-17(4)36)13-18-5-11-21(37)12-6-18)29(43)30-16(3)26(40)33-23(14-24(38)39)27(41)32-19-7-9-20(10-8-19)35(44)45/h5-12,15-16,22-23,25,37H,13-14H2,1-4H3,(H,30,43)(H,31,36)(H,32,41)(H,33,40)(H,34,42)(H,38,39)/t16-,22-,23-,25-/m0/s1
SMILES
[O-][N+](=O)c1ccc(cc1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)Cc2ccc(O)cc2)C(C)C)C)CC(=O)O
Peptide sequence
N-ACETYL-TYR-VAL-ALA-ASP-P-NITROANILIDE
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
GHS PICTOGRAMS
Handling Protect from light and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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