Caspase-10 Substrate AEVD-AFC

SKU
C-2229
  • Formula:C29H34F3N5O11
  • MW:685.6
  • Appearance:Liquid
  • Purity:98% by HPLC
Product Name Qty
Caspase-10 Substrate AEVD-AFC
1000 assays
$608.61
Caspase-10 Substrate AEVD-AFC
200 assays
$284.77
Ready-to-use fluorometric substrate for AEVD-dependent caspases. Activity of AEVD-dependent caspase activity can be quantified by fluorescent detection of free AFC after cleavage from the peptide substrate AEVD-AFC at Ex. = 400 nm and Em. = 505 nm, using a fluorometer or multi-well fluorescence plate reader. Alternatively, a shift in fluorescence from blue to green upon cleavage can be visualized using a hand-held long-UV lamp. Cell Lysis Buffer (Cat. #1067-100, -400), 2X Reaction Buffer (Cat. #1068-20, -80), DTT (1201-1) and other reagents used for caspase assays are also available separately.
More Information
Alternate Name/Synonyms
Ac-AEVD-AFC, Caspase-10 Substrate, Fluorogenic
SKU
C-2229
Chemical Name
Ac-AEVD-AFC, Caspase-10 Substrate, Fluorogenic
Chemical Formula
C29H34F3N5O11
Molecular Weight
685.6
Appearance
Liquid
Purity
98% by HPLC
Stability
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Not Available
MDL NUMBER
MFCD03452804
CHEMACX
X1340733-3
INCHI
InChI=1S/C29H34F3N5O11/c1-12(2)24(37-26(45)18(7-8-21(39)40)35-25(44)13(3)33-14(4)38)28(47)36-19(11-22(41)42)27(46)34-15-5-6-16-17(29(30,31)32)10-23(43)48-20(16)9-15/h5-6,9-10,12-13,18-19,24H,7-8,11H2,1-4H3,(H,33,38)(H,34,46)(H,35,44)(H,36,47)(H,37,45)(H,39,40)(H,41,42)/t13-,18-,19-,24-/m0/s1
SMILES
C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)Nc1ccc2c(cc(=O)oc2c1)C(F)(F)F)NC(=O)C
Peptide sequence
AC-ALA-GLU-VAL-ASP-AFC
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
Promo text for AGS discount
N/A
GHS PICTOGRAMS
Handling Protect from light and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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