Caspase-2 Substrate VDVAD-pNA

SKU
C-2237
  • Formula:C29H41N7O12
  • MW:679.7
  • Appearance:Liquid
  • Purity:98% by HPLC
Product Name Qty
Caspase-2 Substrate VDVAD-pNA
200 assays
$290.47
Caspase-2 Substrate VDVAD-pNA
1000 assays
$643.57

Ready-to-use colorimetric substrate for caspase-2/Ich-1 and related caspases that recognize the amino acid sequence VDVAD. Caspase-2 and related caspase activity can be quantified by detection of free pNA after cleavage from the peptide substrate VDVAD-pNA at OD405 nm using a spectrophotometer or plate reader. The ready-to-use caspase substrate provides an economic alternative for researchers who perform large amount of caspase assays.

More Information
Alternate Name/Synonyms
Ac-VDVAD-pNA, Caspase-2 Substrate, Colorimetric
SKU
C-2237
Chemical Name
Ac-VDVAD-pNA, Caspase-2 Substrate, Colorimetric
Chemical Formula
C29H41N7O12
Molecular Weight
679.7
Appearance
Liquid
Purity
98% by HPLC
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Ac-VDVAD-pNA is a chromogenic substrate for caspase-2
MDL NUMBER
MFCD01862575
CHEMACX
X1206316-2
INCHI
InChI=1S/C29H41N7O12/c1-13(2)23(31-16(6)37)29(46)34-20(12-22(40)41)27(44)35-24(14(3)4)28(45)30-15(5)25(42)33-19(11-21(38)39)26(43)32-17-7-9-18(10-8-17)36(47)48/h7-10,13-15,19-20,23-24H,11-12H2,1-6H3,(H,30,45)(H,31,37)(H,32,43)(H,33,42)(H,34,46)(H,35,44)(H,38,39)(H,40,41)/t15-,19-,20-,23-,24-/m0/s1
SMILES
C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)Nc1ccc(cc1)[N+](=O)[O-])NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)C
Peptide sequence
AC-VAL-ASP-VAL-ALA-ASP-PNA
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
GHS PICTOGRAMS
Handling Protect from light and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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